Sökning: "Varma model"

Visar resultat 1 - 5 av 24 avhandlingar innehållade orden Varma model.

  1. 1. Proteomics-informed analysis of drug disposition in the human liver and small intestine

    Författare :Christine Wegler; Per Artursson; Pär Matsson; Tommy B Andersson; Manthena Varma; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; protein concentration; drug disposition; drug transport; drug metabolism; human small intestine; human liver; human hepatocytes; human liver microsomes; inter-individual variability; drug clearance; obesity; prediction model; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Orally administered drugs are absorbed in the intestine and generally metabolized in the liver. Therefore, understanding factors determining drug distribution and elimination in these tissues is important. LÄS MER

  3. 2. Mechanistic Studies of Dinuclear Metalloenzymes - A Model Approach

    Författare :Håkan Carlsson; Kemiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; models; Enzymes; bioinorganic chemistry; dinuclear; urease; nickel; zinc triphosphoesterase; Oorganisk kemi; Inorganic chemistry;

    Sammanfattning : With the goal to study the mechanisms of dinuclear metalloenzymes, a new line of synthetic and computational models were prepared and studied. Mixed imidazole and carboxylate multidentate complexes were synthesized to better simulate carboxylate-rich ligand environments. LÄS MER

  4. 3. Generative learning management : A dual-role model for creativity in organizations

    Författare :Peter Österberg; Institutionen för psykologi; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Generative learning management; leadership style; goal-setting; decentralization; creativity;

    Sammanfattning : A main purpose of this thesis was to develop a model of leadership style named Generative Learning Management (GLM), thought to influence goal-oriented interpersonal creativity in organizations, and to test this model. Creativity is a complex consisting of both novelty and usefulness and it is a general mental ability that is determined by the interplay between different regions in a normally functioning human brain. LÄS MER

  5. 4. Tree phenology modelling in the boreal and temperate climate zones : Timing of spring and autumn events

    Författare :Cecilia Olsson; Institutionen för naturgeografi och ekosystemvetenskap; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Plant phenology in the boreal and temperate climate zones is synchronised with seasonal changes in temperature and photoperiod. For deciduous trees, timing of budburst and leaf colouring define the growing season length and express adaptations to trade-offs in growth and risks. LÄS MER

  7. 5. Heat Transfer and Energy Efficiency in Infrared Paper Dryers

    Författare :Magnus Pettersson; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; experimental; modelling; electricity; gas; efficiency; energy; drying; dryer; heat transfer; radiation; paper; infrared; IR; coating; Chemical technology and engineering; Kemiteknik och kemisk teknologi;

    Sammanfattning : Infrared (IR) dryers are widely used in the paper industry, mainly in the production of coated paper grades. The thesis deals with various aspects of heat transfer and energy use in infrared heaters and dryers as employed in the paper industry. Both gas-fired and electric IR dryers are considered and compared. LÄS MER