Sökning: "Valerio Leoni"

Hittade 1 avhandling innehållade orden Valerio Leoni.

1. 1. On the possible use of oxysterols for the diagnosis and evaluation of patients with neurological and neurodegenerative diseases

   Författare :Valerio Leoni; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Multiple sclerosis; Alzheimer s disease; oxysterol; central nervous system; gas chromatography-mass spectrometry; blood brain barrier; cholesterol;

   Sammanfattning : Oxysterols are monooxygenated derivatives of cholesterol with a unique ability to pass lipophilic membranes and are involved in a number of elimination pathways for cholesterol. One of the major oxysterols in the circulation, 24S-hydroxycholesterol, is formed exclusively in the brain, mainly in neuronal cells. LÄS MER