Sökning: "VSV-G GLVR-1 amphotropic GALV long-term bone marrow culture NOD SCID retroviral vector hematopoietic"

Hittade 1 avhandling innehållade orden VSV-G GLVR-1 amphotropic GALV long-term bone marrow culture NOD SCID retroviral vector hematopoietic.

  1. 1. Retroviral gene transfer to repopulating hematopoietic cells

    Författare :Thomas Relander; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GLVR-1; VSV-G; amphotropic; GALV; long-term bone marrow culture; NOD SCID; retroviral vector; hematopoietic stem cells; stem cells; gene transfer; gene therapy; fibronectin; Clinical genetics; Klinisk genetik;

    Sammanfattning : Hematopoietic stem cells (HSCs) have the capacity to maintain hematopoiesis throughout life. HSCs are ideal targets for permanent gene transfer, as the transgene will be expressed in all the progeny of the gene-modified stem cells. LÄS MER