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Visar resultat 1 - 5 av 93 avhandlingar som matchar ovanstående sökkriterier.
1. Androgen controlled regulatory systems in prostate cancer : potential new therapeutic targets and prognostic markers
Sammanfattning : BACKGROUND: Prostate cancer is by far the most common cancer among Swedish men. Some patients have an aggressive lethal disease, but the majority of affected men have long expected survival. Unfortunately, the diagnostic tools available are insufficient in predicting disease aggressiveness. Novel prognostic markers are therefore urgently needed. LÄS MER
2. Development and evaluation of new generation vaccines against bovine respiratory syncytial virus
Sammanfattning : Bovine respiratory syncytial virus (BRSV) is a major cause of respiratory disease in cattle worldwide. Improved BRSV vaccines are needed, with better efficacy and longer duration of protection, in particular when used in calves with specific maternally derived antibodies (MDA). LÄS MER
3. Cytokines as diagnostic biomarkers in canine pyometra and sepsis
Sammanfattning : Sepsis is a syndrome with high morbidity, mortality and astronomical health care costs and it is challenging to diagnose both in humans and animals due to the lack of suitable diagnostic biomarkers. Although several types of proteins have been suggested as diagnostic biomarkers of sepsis, none of them were shown to be reliable for routine use in the clinical practice. LÄS MER
4. Investigations of Strategies to Counteract Proinflammatory Cytokines in Experimental Type 1 Diabetes
Sammanfattning : Type 1 diabetes (T1D) is a chronic autoimmune disease targeted against the pancreatic β-cells. Proinflammatory cytokines are considered to play a major role in the destruction of the insulin-producing β-cells. This thesis studied strategies to counteract proinflammatory cytokines in experimental T1D. LÄS MER
5. Bacterial infections in dogs with special reference to urinary tract infections, surgical site infections and methicillin-resistant Staphylococcus pseudintermedius
Sammanfattning : An increase in antimicrobial resistance in canine bacterial pathogens, including multidrug-resistance, has been reported worldwide. Increasing antimicrobial resistance is of concern, not only as it complicates therapy in dogs, but also as it is a public health problem when the pathogens are zoonotic, or the location of resistance genes enables transfer between bacteria of animal and human origin. LÄS MER