Sökning: "VEGFR-1"

Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet VEGFR-1.

  1. 1. Macrophage expression of VEGF and VEGFR-1. Potential involvement in atherogenesis

    Författare :Linda Salomonsson; Göteborgs universitet; []
    Nyckelord :atherosclerosis; macrophages; oxLDL; statins; VEGF; VEGFR-1;

    Sammanfattning : The vascular endothelial growth factor (VEGF) family is a group of proteins which contributes to both neovascularisation and inflammation. Elevated levels of VEGF have been found in subjects with atherosclerosis and correlate to several cardiovascular risk factors, e.g. hypertension and hyperlipidemia. LÄS MER

  3. 2. Renal cell carcinoma : factors of importance for follow-up and survival

    Författare :Farhood Iranparvar Alamdari; Börje Ljungberg; Torgny Rasmuson; Sven Lundstam; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; renal cell carcinoma; follow-up; VEGFR-1; PS; ESR; stage; prognosis; metastasis; surveillance; TNM classification; adrenalectomy; angiogenesis; VEGF; Urology and andrology; Urologi och andrologi;

    Sammanfattning : Background: Renal cell carcinoma (RCC) is most lethal of the urological cancers, with more than 40% dying of the disease. About 30% of the patients have metastases at initial diagnosis and up to 40% undergoing nephrectomy for localized RCC develop metastasis. LÄS MER

  4. 3. Prognostic molecular markers of childhood leukemia

    Författare :Fredrika Gauffin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acute lymphoblastic leukemia; dic 9; 20 ; dried blood spots; Guthrie card; RNA; PTEN; SHP1; VEGF; VEGFR-1; VEGFR-2; immuhistochemistry; tissue micro array;

    Sammanfattning : During the last decades there has been a dramatic increase in survival rates for childhood leukemia, resulting today in an overall survival close to 90 % for children with acute lymphoblastic leukemia (ALL). This accomplishment is largely due to treatment protocols based on careful risk group assessment guiding the type and intensity of the anti-leukemic treatment. LÄS MER

  5. 4. Vascular endothelial growth factor receptors in angiogenesis

    Författare :Kui Huang; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; endothelial cells; VEGF receptor; signal transduction; pertide; angiogenesis; Genetik; Clinical genetics; Klinisk genetik; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Angiogenesis is a process in which new capillaries sprout from preexisting blood vessels. Vascular endothelial growth factor (VEGF) promotes endothelial cell proliferation and migration and thereby stimulates angiogenesis. VEGF receptors (VEGFRs) have been implicated as key regulatory components in endothelial cells. LÄS MER

  7. 5. The role of VEGF family in angiogenesis, tumor growth and metastasis

    Författare :Xiaojuan Yang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tumor growth is dependent on angiogenesis, and cells in tumor tissues produce various angiogenic factors to induce neovascularization. Among tumor-derived angiogenic factors, members of the vascular endothelial growth factor (VEGF) family are most frequently and highly expressed in various solid tumors. LÄS MER