Sökning: "VEGF-B"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet VEGF-B.

  1. 1. Studies of the vascular endothelial growth factors, VEGFs, and their receptors, focusing on VEGF-B

    Författare :Birgitta Olofsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :vasculogenesis; angiogenesis; VEGF; VEGF-B; VEGF receptors; neuropilin;

    Sammanfattning : The inner lining of all blood- and lymphatic vessels are composed of endothelial cells. Their growth and differentiation are in part regulated by polypeptide growth factors and their receptors. LÄS MER

  3. 2. Studies of VEGF-B and novel PDGFs in tumorigenesis and angiogenesis

    Författare :Hong Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The family of VEGF/PDGF growth factors and their receptors are important regulators of tumorigenesis and angiogenesis. VEGFs have been shown to play important roles in development of both blood and lymphatic vessels by effect on endothelia cells. LÄS MER

  4. 3. VEGF-B in islet of langerhans : role in vascular signaling and lipid handling

    Författare :Frank Chenfei Ning; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The discovery of Vascular endothelial growth factor (VEGF)-B’s role in endothelial fatty acid uptake and tissue lipid accumulation opened a new arena for exploration of VEGF-B in lipid metabolism. Indeed, later studies demonstrated the beneficial/therapeutic effects of reducing VEGF-B signaling systemically. LÄS MER

  5. 4. Vascular metabolomics : role of VEGF-B in fatty acid uptake and metabolic disease

    Författare :Carolina Hagberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The incidence of type 2 diabetes and the metabolic syndrome is rapidly increasing among both adults and children worldwide. Type 2 diabetes is strongly associated with obesity and ectopic lipid accumulation. Recent research has shown that peripheral insulin sensitivity is directly impaired by excessive lipid deposition within tissues. LÄS MER

  7. 5. Vascular metabolomics : gene regulation and role of VEGF-B in tissue fatty acid uptake

    Författare :Xun Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Vascular endothelial growth factor B (VEGF‐B) belongs to the VEGF family, which constitutes of five mammalian members. VEGFs exert pivotal roles in the formation, development and maintenance of the vascular and lymphatic vessels. LÄS MER