Sökning: "V. cholerae"

Visar resultat 1 - 5 av 34 avhandlingar innehållade orden V. cholerae.

  1. 1. Roles of membrane vesicles in bacterial pathogenesis

    Författare :Svitlana Vdovikova; Sun Nyunt Wai; Richard Lundmark; Ann-Beth Jonsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane vesicles; autophagy; pore-forming toxin; pore formation; Listeria monocytogenes; Vibrio cholerae; virulence factor; PrtV protease; listeriolysin O; V. cholerae cytolysin; mikrobiologi; Microbiology; molekylärbiologi; Molecular Biology;

    Sammanfattning : The production of membranous vesicles is observed to occur among organisms from all domains of the tree of life spanning prokaryotes (bacteria, archaea) and eukaryotes (plants, animals and fungi). Bacterial release of membrane-derived vesicles (MVs) has been studied most extensively in cases of Gram-negative species and implicating their outer membrane in formation of extracellular MVs. LÄS MER

  2. 2. Modulators of Vibrio cholerae predator interaction and virulence

    Författare :Barbro Lindmark; Sun Nyunt Wai; Kristian Riesbeck; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vibrio cholerae; Caenorhabditis elegans; PrtV; outer membrane vesicles; non-O1 non-O139; serum resistance; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Vibrio cholerae, the causal agent of cholera typically encodes two critical virulence factors: cholera toxin (CT), which is primarily responsible for the diarrhoeal purge, and toxin-co-regulated pilus (TCP), an essential colonisation factor. Nontoxigenic strains expressing TCP can efficiently acquire the CT gene through lysogenic conversion with CTXΦ, a filamentous phage that encodes CT and uses TCP as a receptor. LÄS MER

  3. 3. Regulatory roles of sRNAs in pathogenesis of Vibrio cholerae

    Författare :Dharmesh Sabharwal; Sun Nyunt Wai; Bernt Eric Uhlin; Jörgen Johansson; Cynthia Sharma; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vibrio cholerae; sRNA; Biofilm; OmpT; RbmC; Vrp; VafA; mikrobiologi; Microbiology;

    Sammanfattning : The Gram-negative pathogen Vibrio cholerae uses variety of regulatory molecules to modulate expression of virulence factors. One important regulatory element of microorganisms is small non-coding RNAs (sRNAs), which control various cell functions such as expression of cell membrane proteins, mRNA decay and riboswitches. LÄS MER

  4. 4. Vibrio cholerae modulates the immune defense of human gut mucosa

    Författare :Aziz Bitar; Marie-Louise Hammarström; Sun Nynt Wai; Mikael Rehn; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vibrio cholerae; intestinal epithelial cell; duodenum biopsy; acute cholera; immunomodulation; microRNA; OMV; cytokine; T84 monolayer; miR-146; miR-155; VCC; PrtV; hemolysis; IL-8; TNF-a; IL-1b; IL-18; CCL20; IRAK2; inflammation; mikrobiologi; Microbiology; immunologi; Immunology;

    Sammanfattning : The key function of innate immunity is to sense danger signals and initiate effective responses as a defense mechanism against pathogens. Simultaneously, effector responses must be regulated to avoid excessive inflammation with resulting tissue damage. LÄS MER

  5. 5. Studies on bacterial transmission pathways in a high endemic area, with a focus on Helicobacter pylori

    Författare :Anders Janzon; Göteborgs universitet; []
    Nyckelord :H. pylori; enterotoxigenic E. coli; V. cholerae; real-time PCR; transmission pathways; gastroenteritis; mouse infection models; bacterial gene expression;

    Sammanfattning : Even though half of the world’s population is infected with Helicobacter pylori, which causes gastritis, peptic ulcer and gastric cancer, the transmission routes of these bacteria remain unknown despite extensive epidemiological studies. Enterotoxigenic Escherichia coli (ETEC) and Vibrio cholerae are two of the most common causes of acute watery diarrhea in developing countries. LÄS MER