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Visar resultat 1 - 5 av 161 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Early diagnosis and treatment of prostate cancer : observational studies in the National Prostate Cancer Register of Sweden and the Västerbotten Intervention Project

    Författare :Benny Holmström; Pär Stattin; Håkan Jonsson; Mattias Johansson; Gunnar Aus; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; prostate-specific antigen; single nucleotide polymorphism; Urology and andrology; Urologi och andrologi; Urology; kirurgi; särskilt urologi;

    Sammanfattning : Prostate-specific antigen (PSA) testing has caused a steep increase in the incidence of prostate cancer, especially the incidence of localised low risk disease. In order to decrease the overdiagnosis accompanied by PSA testing, analysis of inherited genetic variants have been suggested as potential tools for clinical assessment of disease risk. LÄS MER

  3. 2. Quality of Life and Functional Outcomes in Men with Localized Prostate Cancer

    Författare :Eva Johansson; Anna Bill-axelson; Anders Widmark; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; radical prostatectomy; watchful waiting; quality of life; erectil dysfunction; androgen deprivation therapy; robot-assisted radical prostatectomy; inguinal hernia; information; randomized; Urology and andrology; Urologi och andrologi; Urologi; Urology;

    Sammanfattning : Quality-of-life and functional outcomes are important in the choice of treatment for men with localized prostate cancer. These issues were investigated in the present thesis. All living 400 men randomized to radical prostatectomy or watchful waiting from 1989 to 1999 in the Scandinavian Prostate Cancer Group Number 4 (SPCG-4) were included. LÄS MER

  4. 3. Outcomes and complications in surgical and urological procedures

    Författare :Karl-Johan Lundström; Pär Nordin; Pär Stattin; Anna Bill Axelson; Thue Bisgaard; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hydrocele; Spermatocele; Groin hernia; prostate biopsy; complication; infection; chronic pain; Urology; kirurgi; särskilt urologi; kirurgi; Surgery;

    Sammanfattning : Background:Minor procedures in surgery and urology such as groin hernia and hydrocele repair, as well as prostate biopsies are very frequently done in routine practice. Complications and insufficient outcomes thus affecting many patients and the cumulative effect of this are of major importance in a population perspective. LÄS MER

  5. 4. Surveillance and follow-up of early prostate cancer

    Författare :Mats Steinholtz Ahlberg; Anna Bill-Axelson; Lars Holmberg; Anna Lantz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; active surveillance; follow-up; biochemical recurrence; triggers for transition to radical treatment; overdiagnosis; overtreatment.; Urologi; Urology;

    Sammanfattning : Active surveillance (AS) for prostate cancer was introduced to address overtreatment resulting from prostate-specific antigen (PSA) testing. Despite advancements such as Magnetic Resonance Imaging (MRI) and targeted biopsies, PSA remains crucial in prostate cancer diagnostics, leading to ongoing challenges of overdiagnosis and overtreatment. LÄS MER

  7. 5. Prognostic factors in prostate cancer with special reference to the effect of hormonal therapy

    Författare :Göran Ahlgren; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; neuroendocrine differentiation; tumour cell proliferation; DNA-ploidy; prostate cancer; prognostic factors; nephrology; Urologi; nefrologi;

    Sammanfattning : We have used image cell analysis to analyse nuclear DNA content on fine needle aspiration biopsies from 96 patients diagnosed to have prostate cancer 1980-81. By stratifying diploid and tetraploid tumours according to a cytometric proliferation index (PI), we suggest a new DNA-classification that is prognostic of death from prostate cancer in multivariate analysis including conventional prognostic factors. LÄS MER