Sökning: "Uppsala universitet medicine"

Visar resultat 21 - 25 av 4834 avhandlingar innehållade orden Uppsala universitet medicine.

  1. 21. Molecular Targets in Autoimmune Polyendocrine Syndrome Type1 and Their Clinical Implications

    Författare :Mohammad Alimohammadi; Olle Kämpe; Anna Lobell; Fredrik Rorsman; Tommy Olsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmunity; autoantibodies; endocrinology; parathyroid; hypoparathyroidism; Addison s disease; pulmonary symptoms; NALP; NALP5; NLR; KCNRG; Molecular medicine; Molekylär medicin;

    Sammanfattning : Autoimmune diseases occur when the immune system attacks and destroys healthy body tissue. Autoimmunity is known to cause a wide range of disorders, and is suspected to be responsible for many more. Most autoimmune disorders are chronic and cause severe morbidity for the patients, and are also costly for society. LÄS MER

  3. 22. Polycystic Ovary Syndrome and Pregnancy : Prenatal Exposures and Pregnancy Complications

    Författare :Heiddis Valgeirsdóttir; Anna-Karin Wikström; Inger Sundström Poromaa; Theodora Kunovac Kallak; Marie Blomberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Polycystic ovary syndrome; PCOS; pregnancy; epidemiology; prenatal exposures; pregnancy complications; Anti-Müllerian hormone; AMH; preterm birth; stillbirth; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of fertile age. The aetiology of PCOS is not fully understood and might be affected by foetal exposures. Women with PCOS have an increased risk of pregnancy complications, but information on rare severe complications is scarce. LÄS MER

  4. 23. Superparamagnetic iron oxide nanoparticles, a novel tracer in breast cancer surgery

    Författare :Abdi-Fatah Hersi; Staffan Eriksson; Fredrik Wärnberg; Andreas Karakatsanis; Thorsten Kühn; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast Cancer; superparamagnetic iron oxide nanoparticles; SPIO; magnetic seed; magnetic surgery; sentinel node; sentinel node biopsy; nonpalpable; ductal carcinoma in situ; DCIS; Surgery; Kirurgi;

    Sammanfattning : The most common surgical choice of treatment in breast cancer is breast-conserving surgery (BCS) together with sentinel lymph node biopsy (SNB). Around 10% of breast cancer diagnosis are ductal carcinoma in situ (DCIS). Superparamagnetic iron oxide nanoparticles (SPIO) are a novel tracer for sentinel lymph node (SN) detection. LÄS MER

  5. 24. Positron Emission Tomography (PET) Studies in Anxiety Disorders

    Författare :Åsa Michelgård Palmquist; Mats Fredrikson; Lars von Knorring; Hans Ågren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Positron emission tomography; PET; amygdala; fear; anxiety; anxiety disorders; specific phobia; social phobia; posttraumatic stress disorder; PTSD; regional cerebral blood flow; rCBF; substance P; SP; neurokinin 1 receptor; NK1; GR205171; STAI-S; Psychiatry; Psykiatri; Neurobiology; Neurobiologi; Neuroscience; Neurovetenskap; Experimental brain research; Experimentell hjärnforskning; Molecular neurobiology; Molekylär neurobiologi; Radiation biology; Strålningsbiologi; Neurobiology; Neurobiologi; Neurobiology; Neurobiologi;

    Sammanfattning : Anxiety disorders are very common and the primary feature is abnormal or inappropriate anxiety. Fear and anxiety is often mediated by the amygdala, a brain structure rich in substance P (SP) and neurokinin 1 (NK1) receptors. LÄS MER

  7. 25. Investigations of Strategies to Counteract Proinflammatory Cytokines in Experimental Type 1 Diabetes

    Författare :Andreas Börjesson; Stellan Sandler; Annika Carlsson; Jens Nielsen; Uppsala universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Type 1 diabetes; proinflammatory cytokines; SOCS-3; pancreatic islets; inducible nitric oxide synthase; insulin secretion; NOD mice; islet transplantation; proinsulin conversion; streptozotocin; prolactin; Medicine; Medicin;

    Sammanfattning : Type 1 diabetes (T1D) is a chronic autoimmune disease targeted against the pancreatic β-cells. Proinflammatory cytokines are considered to play a major role in the destruction of the insulin-producing β-cells. This thesis studied strategies to counteract proinflammatory cytokines in experimental T1D. LÄS MER