Sökning: "Ultrasensitive Analysis"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Ultrasensitive Analysis.

1. 1. Capacitive Biosensor - A Tool for Ultrasensitive Analysis : Application in Clinical Analysis and Process Monitoring

   Författare :Kosin Teeparuksapun; Bioteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Capacitive Biosensor; Ultrasensitive Analysis; Clinical Analysis; Bioprocess Monitoring; Human Serum Albumin; HIV-1 p24; Host Cell Proteins; Protein A; Current Pulse;

   Sammanfattning : Increasing demands for highly sensitive, accurate, fast and portable analytical assays have led to the development of new analytical tools. The integration of highly specific biological sensing elements and appropriate transducers has enabled design of even more efficient biosensor devices for the detection of target substances. LÄS MER

3. 2. Next generation molecular diagnostics using ultrasensitive sequencing

   Författare :Stefan Filges; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid biopsy; cell-free DNA; circulating tumor DNA; molecular diagnostics; next-generation sequencing; unique molecular identifiers; melanoma;

   Sammanfattning : Massively parallel sequencing enables the exploration of the genetic heterogeneity within microbial, viral and tumor cell populations. Detecting circulating tumor DNA in blood and other body fluids has the potential to revolutionize molecular diagnostics. LÄS MER

4. 3. Development of an Ultrasensitive Capacitive DNA-sensor: A promising tool towards microbial diagnostics

   Författare :Ally Mahadhy; Bioteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Capacitive DNA-sensor; Enterobacteriaceae; mecA gene; Methicillin resistance; automated sequential injection analysis; sandwichhybridization; elevated temperature; polytyramine;

   Sammanfattning : Fast and sensitive detection of pathogenic microbial cells is a highly important task in medical diagnostics, environmental analysis and evaluation of food safety. Accordingly, the idea of microorganism identification by the recognition of specific DNA sequence using electrochemical technique is one of the leading researches in the development of diagnostic devices. LÄS MER

5. 4. Ultrasensitive DNA sequencing using liquid biopsies enables precision medicine

   Författare :Gustav Johansson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liquid biopsy; cell-free DNA; immune repertoire; next-generation sequencing; unique molecule identifier; GIST; γδ T cell;

   Sammanfattning : Liquid biopsies are minimally invasive and allow repetitive sampling of body fluids. Analysis of cell-free tumor DNA in liquid biopsies can be used as a biomarker for cancer. However, in most clinically relevant liquid biopsies, cell-free DNA is present at low concentrations, contains minute tumor allele frequencies, and is highly fragmented. LÄS MER

7. 5. Pharmaceutical and Biomedical Applications of Spectroscopy in the Photon Migration Regime

   Författare :Tomas Svensson; Atomfysik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Porosimetry; Biomedical optics; Pharmaceutical analysis; Monte Carlo; Scattering media; Photon migration; Laser spectroscopy; High-resolution spectroscopy; Time-resolved spectroscopy; Time-of-flight;

   Sammanfattning : The present thesis is devoted to two different matters: One part is the development of a novel optical technique for characterisation of solid pharmaceutical materials. The other part being the continued development of photon time-of-flight spectroscopy, as well as exploration of new application areas of this method. LÄS MER