Sökning: "Ulrika Nyman"

Hittade 2 avhandlingar innehållade orden Ulrika Nyman.

  1. 1. On the structure-function relationship of p73

    Författare :Ulrika Nyman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : The development of multicellular organisms requires a balance between the cellular processes of proliferation, differentiation and death. These processes are important throughout the whole life of the organism. Daily, the DNA in our cells is under attack by agents that can cause damage. LÄS MER

  2. 2. p73 - regulator of differentiation and apoptotic cell death

    Författare :Ulrika Nyman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Neoplasia is characterized by cells' loss of self-control due to deregulated apoptotic and cell proliferation pathways. Anticancer treatments aim to induce either cell cycle arrest or apoptosis, and these effects are in most part mediated by proteins, like p53 and p73, which are involved in and able to mediate both processes. LÄS MER