Sökning: "UVR"
Visar resultat 1 - 5 av 38 avhandlingar innehållade ordet UVR.
1. Malignant melanoma-Risk factors and the CDKN2A mutation in relation to phenotypes and other cancers
Sammanfattning : Background: Cutaneous malignant melanoma (CMM) is an increasingly common cancer in fair-skinned people. The purpose of this thesis was to study high-risk patients with multiple tumours including a CMM, high-risk families with the unique Swedish germline mutation in CDKN2A(113insArg), as well as study risk factors for CMM in women. LÄS MER
2. Prevention of Experimental Cataract Induced by UVR
Sammanfattning : Cataract is the leading cause of blindness in the world and is defined by opacification of the normally transparent lens of the eye. The major avoidable cause of cataract is ultraviolet radiation (UVR), but no current strategies have been developed to prevent the onset of cataract. LÄS MER
3. Influence of exposure patterns and oxidation in UVR-induced cataract
Sammanfattning : Background: Ultraviolet radiation (UVR) is one among a number of possible factors that may lead to the development of cataract. Whereas induction of cataract as the result of onetime exposure to UVR has been studied extensively, the data on lens damage resulting from repeated exposures to UVR are scarce. LÄS MER
4. Cataract induced by UVR-B 300nm : characterization and genetic modulation of the lens sensitivity to oxidative stress
Sammanfattning : Cataract is defined as an opacification of the lens resulting in visual impairment. Worldwide, it is the number one cause of blindness and there are currently no strategies to prevent the onset of the disease. Cataract surgery is the most commonly performed elective intervention in industrialized countries. LÄS MER
5. Ultraviolet radiation and cornea
Sammanfattning : Background: Acute exposure of the mammalian eye to UVR results in development of photokeratitis after a period of a few hours. Chronic exposure to UVR is associated with an increased risk of several corneal disorders, including pterygium, climatic droplet keratopathy, and climatic proteoglycan stromal keratopathy. LÄS MER