Sökning: "UVC"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet UVC.

  1. 1. Interplay between Transcription and Homologous Recombination in the Presence of DNA Damage

    Författare :Ivaylo Stoimenov; Thomas Helleday; Niklas Schultz; Natalia Issaeva; Thierry Nouspikel; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; homologous recombination; transcription; DRB; UVC; 6-thioguanine; mammalian cells; BRCA1; BRCA2; PARP inhibitors; XP-V; Molecular biology; Molekylärbiologi; molekylärgenetik; Molecular Genetics;

    Sammanfattning : The biochemical processes of DNA repair, replication and recombination compete for the same substrate, the DNA molecule. This competition is natural, as each process requires the same template. In order to resolve possible conflicts between these processes, when they take place on a particular stretch of DNA, certain crosstalk is expected. LÄS MER

  3. 2. Pathogen colonisation, transmission and infection control measures in burn patients

    Författare :Marie Lindblad; Fredrik Huss; Jyrki Vuola; Uppsala universitet; []
    Nyckelord :Whole-genome sequencing; Burn injury; Acinetobacter baumannii outbreak; infection control prevention; UVC decontamination;

    Sammanfattning : Burn patients are susceptible to infections due to impaired natural defences when the epidermal barrier is damaged. Moreover, the trauma affects the patient's immune system through local and systemic inflammatory reactions. Adding to that, the need for intensive care treatment with multiple surgical interventions increases the risk of infection. LÄS MER

  4. 3. Light’EM up! : structural characterization of light-driven membrane protein complexes by cryogenic electron microscopy

    Författare :André Tomás Graça; Wolfgang P. Schröder; Johannes Messinger; Karina Persson; Werner Kühlbrandt; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 3D reconstruction; Arabidopsis thaliana; assembly; chlorophyll; cryo-EM; cyanobacteria; Deinococus radiodurans; electron; land plants; membrane protein complexes; Photosystem II; proton; single-particle analysis; S-Layer Deinoxanthin Binding Complex SDBC ; water.; Biochemistry; biokemi; biologisk kemi; biological chemistry;

    Sammanfattning : Photosynthesis is probably the most important process for allowing life to develop into the diverse forms we see today. In this process, solar radiation is used to convert CO2 into biomass. From this process, we obtain oxygen to breathe, sources of food (plant biomass), and the potential for clean and sustainable energy. LÄS MER

  5. 4. The role of MTH1 in ultraviolet radiation-induced mutagenesis

    Författare :Asal Fotouhi; Siamak Haghdoost; Harry Vrieling; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ultraviolet radiation; MTH1; reactive oxygen species; 8-oxo-dGTP; 2-OH-dATP; micronucleus; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Ultraviolet radiation (UVR) is known to be highly mutagenic. What types of DNA lesions that are induced by different UVR wavelengths are still a matter of debate. UVR induces mutagenesis mostly by the formation of photoproducts and the induction of reactive oxygen species (ROS). LÄS MER

  7. 5. MOLECULAR AND GENETIC STUDIES OF DLG2 IN NEUROBLASTOMA AND COLORECTAL CANCER

    Författare :Simon Keane; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Neural crest; Neuroblastoma; colon cancer; DLG2; MYCN; LIN7A; inflammation;

    Sammanfattning : Neuroblastoma is one of the most common extra cranial solid tumors in children. It is one of the most common causes of death amongst the pediatric malignancies. LÄS MER