Sökning: "U87.CD4 cells"

Hittade 2 avhandlingar innehållade orden U87.CD4 cells.

  1. 1. Coreceptor usage and sensitivity to neutralization of HIV-1 and HIV-2

    Författare :Yu Shi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; HIV-2; pathogenesis; neutralization; coreceptor usage; envelop sequence; glycosylation; U87.CD4 cells; GHOST 3 cells; CCR5; CXCR4;

    Sammanfattning : The aim of this project was to study neutralization and coreceptor use in HIV-1 and HIV-2. The first step was to develop a simple and standardized assay for detection and quantification of HIV- 1 neutralizing activity in human sera. LÄS MER

  3. 2. HIV-1 infection during pregnancy and in children : significance of HIV-1 variability and the placental barrier

    Författare :Charlotte Casper; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :biological phenotype; genetic subtype; chemokine receptor; coreceptor; mother- to-child transmission; placenta; disease progression; child; pregnancy;

    Sammanfattning : With the global increase in human immunodeficiency virus 1 (HIV-1) infection in women of childbearing age, there has also been an alarming increase in the number of mother-to-child transmissions of HIV-1. Although antiretroviral therapy and Cesarian section have been demonstrated to significantly decrease the vertical transmission rate of, these interventions are not widely available in the developing world. LÄS MER