Sökning: "Tyrosine and alanine transport"

Hittade 2 avhandlingar innehållade orden Tyrosine and alanine transport.

1. 1. Amino acid transport and receptor binding properties in neuropsychiatric disorders using the fibroblast cell model

   Författare :Jessica Johansson; Nikolaos Venizelos; Lars Oreland; Örebro universitet; []
   Nyckelord :Fibroblasts; Bipolar disorder; ADHD; Tyrosine; Tryptophan; Alanine; Transport; mAChRs; Biomedicin; Biomedicine;

   Sammanfattning : Altered transport of the catecholamines and serotonin precursor amino acids tyrosine and tryptophan, might be one explanation for the dysfunctional neurotransmission implicated in the pathophysiology of bipolar disorder and Attention Deficit/Hyperactivity Disorder (ADHD). In previous studies, an altered amino acid transport has been found in schizophrenia and autism, when using the fibroblast cell model. LÄS MER

3. 2. Functional Characterization of Tyrosine Transporters in fibroblast from Healthy Controls and Schizophrenic Patients

   Författare :Ravi Vumma; Nikolaos Venizelos; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fibroblasts; Schizophrenia; Precursor of Dopamine; Biological Transport; Active cellphysiology; Tyrosine and alanine transport; System-L; LAT1; LAT2; LAT3; LAT4; MEDICINE; MEDICIN; Internal medicine; Invärtesmedicin; Neurology; Neurologi; Neurology; Neurologi;

   Sammanfattning : Cultured human fibroblasts offer an advantageous system to investigate the amino acid transport properties without confounding the affects of disease state and its treatment in many systemic psychiatric disorders. In previous studies, fibroblast cells have been used to investigate the tyrosine transport across plasma membranes in patients with schizophrenia and autism with out characterizing the particular amino acid transporters. LÄS MER