Sökning: "Type-2 diabetes"

Visar resultat 21 - 25 av 740 avhandlingar innehållade orden Type-2 diabetes.

  1. 21. Genetic Factors Contributing to Hypertension. With Emphasis on Hypertension in Type 2 Diabetes

    Författare :Kristina Bengtsson Boström; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; diabetology; primary care; genetics; Hypertension; type 2 diabetes;

    Sammanfattning : The causes of hypertension (HT) and type 2 diabetes (T2DM) are mainly unknown, but they arise from interplay between several genetic and environmental factors. The aim of this thesis was to investigate whether polymorphisms in putative candidate genes for HT increase the susceptibility to HT and/or T2DM. LÄS MER

  3. 22. Assessment and Treatment of Impaired Insulin- Secretion and Action in Type 2 Diabetes

    Författare :Mozhgan Dorkhan; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes; insulin secretion; glucagon test; insulin resistance; insulin glargine; insulin tolerance test; thiazolidinediones; natriuretic peptides; adiponectin; thyroid associated ophthalmopathy; proinsulin;

    Sammanfattning : Type 2 diabetes (T2D) is a disease characterised by varying degrees of defect in insulin secretion and insulin sensitivity and associated with increased morbidity and mortality. Optimal glycaemic control reduces the progression of diabetic complications. LÄS MER

  4. 23. FOXC2 and CAPN10 as candidate genes for obesity, insulin resistance and type 2 diabetes

    Författare :Emma A Nilsson; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper; Biomedical sciences; Type 2 diabetes; Genetics; Obesity;

    Sammanfattning : The worldwide prevalence of obesity and type 2 diabetes is increasing rapidly. Both disorders depend on genetic and environmental factors. The studies included in this thesis investigated the possible association of the FOXC2 and CAPN10 genes with obesity, insulin resistance, type 2 diabetes, and related phenotypes. LÄS MER

  5. 24. Brain function and glucocorticoids in obesity and type 2 diabetes including effects of lifestyle interventions

    Författare :Andreas Stomby; Tommy Olsson; Mats Ryberg; Carl-Johan Boraxbekk; Alasdair MacLullich; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; type 2 diabetes; glucocorticoid; cortisol; 11beta hydroxysteroid dehydrogenase type 1; episodic memory; functional magnetic resonance imaging; paleolithic diet; exercise; Internal Medicine; invärtesmedicin; medicin; Medicine;

    Sammanfattning : Background Obesity and associated metabolic dysregulation are linked to impaired cognitive function and alterations in brain structure, which increases the risk of age-related dementia. Increased glucocorticoid (GC) exposure may be a potential mediator of these negative effects on the brain. LÄS MER

  7. 25. Bariatric surgery as treatment of type 2 diabetes – clinical and mechanistic aspects

    Författare :Petros Katsogiannos; Jan Eriksson; Magnus Sundbom; Per-Ola Carlsson; Daniel Andersson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Roux-en-y gastric bypass; Type 2 diabetes; incretins; cytokines; adipokines; adipose tissue; heart rate variability; quality of life.; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Bariatric surgery can rapidly improve glycemic control and cardiovascular risk factors in patients with T2D and obesity. These improvements appear to be partly independent of weight loss, however, the underlying mechanisms remain incompletely understood. LÄS MER