Sökning: "Type I markers"

Visar resultat 6 - 10 av 362 avhandlingar innehållade orden Type I markers.

  1. 6. Identifying risk of type 2 diabetes : epidemiologic perspectives from biomarkers to lifestyle

    Författare :Margareta Norberg; Lars Weinehall; Jan W Eriksson; Christer Andersson; Mai-Lis Hellénius; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes mellitus; metabolic syndrome; prediction; stress; social support; smokeless tobacco; risk; obesity; lifestyle; psychosocial; clinical markers; case-referent study; cohort study; Epidemiology; Epidemiologi;

    Sammanfattning : Type 2 diabetes is a significant health problem because of its high prevalence and strong association with cardiovascular morbidity and mortality. An increase of type 2 diabetes is predicted due to increasing obesity and sedentary lifestyle habits. LÄS MER

  3. 7. The role of stroma-derived substances in breast cancer progression and their function as tumour markers

    Författare :Malin Jansson; Malin Sund; Daniel Öhlund; Ola Billing; Emma Niméus; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; perlecan; type IV collagen; type I collagen; extracellular matrix; tumour biomarkers; Surgery; kirurgi;

    Sammanfattning : Background: In 2020, more than 2,260,000 women were diagnosed with breast cancer. Most patients are cured with surgery and adjuvant treatment, but despite that, approximately 700,000 women die of the disease every year. The historical focus on breast cancer progression has been on the malignant epithelial cell. LÄS MER

  4. 8. Genetic Analyses of Multiple Sclerosis and Systemic Lupus Erythematosus : From Single Markers to Genome-Wide Data

    Författare :Johanna K Sandling; Ann-Christine Syvänen; Lovisa Lovmar; Joseph Terwilliger; Javier Martín Ibáñez; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic lupus erythematosus; Multiple Sclerosis; Association study; Type I interferon system; Single nucleotide polymorphism; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molekylär medicin; Molecular Medicine;

    Sammanfattning : In autoimmune diseases an individual’s immune system becomes targeted at the body’s own healthy cells. The aim of this thesis was to identify genetic risk factors for the two autoimmune diseases multiple sclerosis (MS) and systemic lupus erythematosus (SLE). LÄS MER

  5. 9. Pinpointing biomarkers of importance for children with combined type 1 diabetes and celiac disease

    Författare :Andrea Tompa; Maria Faresjö; Karin Åkesson; Mikael Karlsson; Jönköping University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; celiac disease; children; biomarkers; immune markers; flow cytometry; cryopreservation; T cells; T-regulatory cells; B cells; B-regulatory cells; cytokines; chemokines; acute phase proteins; adipocytokines; matrix metalloproteinases;

    Sammanfattning : Type 1 diabetes (T1D) and celiac disease are both characterized by an autoimmune feature. The diseases also share the same risk genes, and thereby patients have an increased risk of developing the other disease subsequently. LÄS MER

  7. 10. Risk markers and incidence of atrial fibrillation in northern Sweden

    Författare :Cecilia Johansson; Lars Johansson; Jonas Andersson; Marcus Lind; Marie Eriksson; Mårten Rosenqvist; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atrial fibrillation; atrial flutter; incidence; provoking factors; types of atiral fibrillation; stroke risk; alcohol consumption; problem drinking; weight; height; weight change; normal blood pressure; high normal blood pressure; Förmaksflimmer; förmaksfladder; incidens; provocerande faktorer; typer av förmaksflimmer; strokerisk; alkoholkonsumtion; alkoholproblem; vikt; längd; viktförändring; normalt blodtryck; högt normalt blodtryck; medicin; Medicine;

    Sammanfattning : Background: Atrial fibrillation (AF) is the most common clinically significant arrythmia with a prevalence of approximately 3% in the general population. Less is known about the incidence of AF. In order to reduce the incidence of AF, it is of essence to identify modifiable risk factors for the disease. LÄS MER