Sökning: "Type 2 diabetes"

Visar resultat 21 - 25 av 952 avhandlingar innehållade orden Type 2 diabetes.

  1. 21. Genetics of type 2 diabetes and the metabolic syndrome

    Författare :Mia Klannemark; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; PDE3B; PPARG; LPL; metabolic syndrome; diabetes; genetic; HSL; UCP2; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Type 2 diabetes and the metabolic syndrome are highly prevalent disorders with severe complications such as cardiovascular disease. The aetiology of type 2 diabetes and the metabolic syndrome is not known, but the interaction between genetic factors and environmental triggers is important. LÄS MER

  3. 22. Exploring food concepts for the prevention of type 2 diabetes

    Författare :Ulrika Axling; Molekylär endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glycaemic index; whole grain; Type 2 diabetes; obesity; rose hip;

    Sammanfattning : There is currently a dramatic and global increase in obesity, type 2 diabetes (T2D) and associated metabolic disorders. T2D can be delayed or prevented in individuals at risk and identifying and developing new food concepts for the prevention of obesity and T2D is of utmost importance. LÄS MER

  4. 23. Genetic and immunological risk factors of gestational diabetes mellitus

    Författare :Nael Shaat; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GDM; Association; genetics; gestational diabetes mellitus metabolic syndrome; MODY; type 1 diabetes; risk factors; type 2 diabetes; Endocrinology; diabetology; secreting systems; autoimmunity; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Gestational diabetes mellitus (GDM) is a heterogeneous disorder that is defined as carbohydrate intolerance with onset or first recognition during pregnancy. Impaired beta-cell function and insulin resistance are the hallmarks of GDM. LÄS MER

  5. 24. Genetic Factors Contributing to Hypertension. With Emphasis on Hypertension in Type 2 Diabetes

    Författare :Kristina Bengtsson Boström; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; diabetology; primary care; genetics; Hypertension; type 2 diabetes;

    Sammanfattning : The causes of hypertension (HT) and type 2 diabetes (T2DM) are mainly unknown, but they arise from interplay between several genetic and environmental factors. The aim of this thesis was to investigate whether polymorphisms in putative candidate genes for HT increase the susceptibility to HT and/or T2DM. LÄS MER

  7. 25. Genetics of Diabetes Subtypes. Characterization of novel cluster-based diabetes subtypes

    Författare :Dina Mansour Aly; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Precision medicine; Diabetes Subclassification; genome-wide association studies; GWAS; genetic risk scores; GRS; chronic kidney disease; CKD; diabetic kidney disease; DKD; Estimated glomerular filtration rate; eGFR; ANDIS; diabetes; diabetics;

    Sammanfattning : BACKGROUND: Type 2 diabetes (T2D) has been reproducibly clustered into five subtypes based on six-clinical variables; age at diabetes onset, body mass index (BMI), Glutamic acid decarboxylase autoantibodies (GADA), glycated hemoglobin (HbA1c) and insulin secretion and resistance estimated as HOMA2B and HOMA2IR derived from fasting glucose and Cpeptide. These subtypes have different disease progression and risk of complications. LÄS MER