Sökning: "Tumour immunology"

Visar resultat 31 - 35 av 37 avhandlingar innehållade orden Tumour immunology.

  1. 31. Soluble intercellular and vascular cell adhesion molecules-1 in lymphoid neoplasms : A clinical and prognostic study of Hodgkin's disease, non-Hodgkin's lymphomas and chronic B-lymphocytic leukaemia

    Författare :Ilse Christiansen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Hodgkin s disease; non-Hodgkin s lymphomas; chronic lymphocytic leukaemia; sICAM-1; sVCAM-1; prognostic markers; VCAM-1; ICAM-1; Hodgkin cell lines; Onkologi; Oncology; Onkologi; Clinical Immunology; klinisk immunologi;

    Sammanfattning : The interaction of soluble adhesion molecules with adhesion ligands expressed by immunological cells interfere with the cell-cell adhesion essential for the signal transductions that initiate immunological responses. Preliminary data suggest that soluble adhesion molecules also promote angiogenesis. LÄS MER

  3. 32. The immune microenvironment in mantle cell lymphoma : Targeted liquid and spatial proteomic analyses

    Författare :Lavanya Lokhande; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mantle cell lymphoma MCL ; proteomic analyses; spatial analysis; Biomarker discovery; immune microenviroment; serum proteomics;

    Sammanfattning : The complex interplay of the tumour and immune cells affects tumour growth, progression, and response to treatment. Restorationof effective immune response forms the basis of onco-immunology, which further enabled the development of immunotherapy. LÄS MER

  4. 33. HLA-A*02 and its prognostic traits in cancer : an immunological biomarker as a tool towards individualised cancer therapy

    Författare :Lisa Villabona; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis is based on the findings that HLA-A*02, a common allele in the Swedish population, has a decreasing frequency in the European continent in relation to geographic latitude. Furthermore, mortality of ovarian cancer correlates to the HLA-A*02 frequency and geographic latitude. LÄS MER

  5. 34. Methodological approaches towards personalised cancer medicine

    Författare :Michael Mints; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite advances in diagnostics and treatments, many cancer patients have poor survival rates. Tumours develop drug resistance followed by metastasis, and survivors suffer from treatment side-effects. LÄS MER

  7. 35. Vaccination in gastrointestinal cancer

    Författare :Caroline Staff; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :CEA;

    Sammanfattning : Advances in immunology have increased the possibility to develop therapeutic cancer vaccines (TCV), as a complementary approach to standard treatment. The goal of a successful cancer vaccine is to induce a potent long-lasting immune response against the tumour with limited toxicity on normal cells. LÄS MER