Sökning: "Tumour angiogenesis"

Visar resultat 1 - 5 av 52 avhandlingar innehållade orden Tumour angiogenesis.

  1. 1. Head and Neck Cancer : Factors Affecting Tumour Growth

    Författare :Kaarina Sundelin; Elisabeth Paulette-Hultcrantz; Karin Öllinger; Karin Roberg; Hans Gustafsson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Head and neck cancer; Chemoradiotherapy; Tumour; Malignant salivary; Metallothionein; Neo-angiogenesis; Metastases; Cytokine tumour necrosis factor-alpha; hepatocyte growth factor; Oncology; Onkologi;

    Sammanfattning : Head and neck cancer is the fifth most common cancer worldwide with an estimated annual global incidence of over 500 000 cases. These malignant tumours develop in the mucosal linings of the upper respiratory tract or in the salivary glands. The most common sites are in the oral cavity and larynx. LÄS MER

  3. 2. The functional role of neural cell adhesion molecule in pathological angiogenesis

    Författare :Joakim Håkansson; Göteborgs universitet; []
    Nyckelord :N-CAM; pericytes; tumour; PDGF-B; ECM; retina; angiogenesis;

    Sammanfattning : .... LÄS MER

  4. 3. Molecular Regulation of Angiogenesis

    Författare :Sofie Mellberg; Lena Claesson-Welsh; Frank Böhmer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endothelial morphogenesis; VEGFR-2; protein tyrosine phosphatase; VE-PTP; PTPRB; endocan; ESM-1; angiogenesis; Molecular medicine; Molekylär medicin;

    Sammanfattning : Angiogenesis, de novo formation of blood vessels from the pre-existing vasculature, is crucial in embryo development, and in processes in the adult such as wound healing and ovulation. Angiogenesis is also involved in pathological conditions such as cancer and chronic inflammatory diseases, which are propagated by dysregulated, excess angiogenesis. LÄS MER

  5. 4. Experimental therapies of malignant glioma : with emphasis on angiogenesis inhibition

    Författare :Maria Sandström; Roger Henriksson; Mikael Johansson; Anja Smits; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; angiogenesis; VEGF; tyrosinekinaseinhibitor; ZD6474; plasminogenactivator; tPA; uPA; proteomics; Oncology; Onkologi;

    Sammanfattning : Malignant glioma consists of a group of diseases where the localisation and the nature of the disease makes treatment an extreme challenge. Two important biological features of malignant glioma cells are their infiltrative growth and their ability to induce angiogenesis. LÄS MER

  7. 5. Tumour vasculature, oxygenation and radiosensitivity - a numerical modelling study

    Författare :Jakob Heydorn Lagerlöf; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; Dosimetry; Hypoxia; Modelling; Radionuclide therapy; Radiotherapy; Tumour Control Probability;

    Sammanfattning : This thesis aims to investigate theoretically how parameters such as vessel density, blood oxygenation, blood velocity, spatial oxygen variation along vessels, tissue oxygen consumption and their distributions in uence the radiosensitivity of tumours. Numerical calculations are made in Matlab using voxel-based models. LÄS MER