Sökning: "Tumor-associated antigen"

Visar resultat 1 - 5 av 33 avhandlingar innehållade orden Tumor-associated antigen.

  1. 1. Vaccine Therapy of Colorectal Cancer Patients with Tumor Associated Antigens

    Författare :Gustav Ullenhag; Håkan Mellstedt; Carl Magnusson; Bengt Glimelius; Torgny Stigbrand; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Oncology; Colorectal cancer; GM-CSF; vaccination; CEA; ALVAC-KSA; IgG subclass; epitopes; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : In this thesis, two different vaccines were evaluated as adjuvant therapy for patients with colorectal cancer. The ability of the two candidate vaccines to generate antigen-specific cellular and humoral responses, respectively, was studied. LÄS MER

  3. 2. Some New Methods in Sialic Acid Chemistry

    Författare :Teddy Ercegovic; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; thioglycoside promoter; ganglioside; Tumor-associated antigen; lactam; lactone; sialic acid; N-acetylneuraminic acid; Neu5Ac; sialyl donor; auxiliary group; 3- S -phenylthio; bis-sialic acid lactam; 3- S -phenylseleno; silver trifluoromethanesulfonate; iodine monochloride; Organic chemistry; Organisk kemi;

    Sammanfattning : Gangliosides (G) are sialic acid-containing cell surface glycosphingolipids capable of forming lactones, i.e. inner esters. Some gangliosides are tumor-associated antigens, and they may serve as immunogens in their lactone form, where the latter is comparatively more abundant on the surface of malignant cells. LÄS MER

  4. 3. MHC class I restricted and antigen-specific TCRs against viral and tumor-associated antigens (TAAs) for future biological therapy

    Författare :Zhenjiang Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Adoptive cellular immunotherapy (ACT) refers to the process of transferring immune cells (autologous or allogeneic) directly to the host as a treatment for cancer or infectious diseases. The effector cells could be antigen-specific, like T cells, or non-specific, such as NK cells or lymphokine-activated killer (LAK) cells. LÄS MER

  5. 4. In vitro studies of natural and tumor-associated immunity in patients with transitional cell carcinoma of the urinary bladder

    Författare :Marita Troye-Blomberg; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Peripheral blood lymphocytes (PBL) from patients with transitional cell carcinoma of the urinary bladder (TCC-bladder) were studied using a SlCr-release assay for their in vitro cytotoxicity against a panel of allogeneic tissue culture cell lines of TCC-bladder and other origins. Control PBL were obtained from four different groups of donors. LÄS MER

  7. 5. Synthesis of oligosaccharide derivatives corresponding to tumor-associated glycolipids, to the Salmonella lipopolysaccharide outer core and to the Haemophilus influenzae type c capsular antigen

    Författare :Anne-Charlotte Helland; Stockholms universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER