Sökning: "Tumor heterogeneity"
Visar resultat 21 - 25 av 139 avhandlingar innehållade orden Tumor heterogeneity.
21. Role of MYCN in retinoblastoma : From carcinogenesis to tumor progression
Sammanfattning : Retinoblastoma, a pediatric malignancy of the retina, is primarily driven by the bi-allelic inactivation of the RB1gene. However, a subset of cases are characterized by proficient RB1 functions but with MYCN copy number mutations, suggesting an alternative oncogenic mechanism in the absence of RB1 mutations. LÄS MER
22. Developing novel diffusion MRI methods for comprehensive analysis of restricted and anisotropic self-diffusion system
Sammanfattning : Diffusion MRI is a non-invasive imaging technique used to study the microstructural properties of biological tissues by observing the self-diffusion of water molecules. Traditional diffusion MRI methods, based on the pulsed gradient spin-echo sequence, employ magnetic field gradients to encode information about translational motion. LÄS MER
23. New Molecular Approaches to Glioblastoma Therapy
Sammanfattning : Glioblastoma (GBM) is the most common high-grade brain tumor diagnosed in patients who are more than 50 years of age. The standard of care treatment is surgery, followed by radiotherapy and chemotherapy. The median life expectancy of patients is only between 12 to 15 months after receiving current treatment regimes. LÄS MER
24. Massively Parallel Sequencing of Gene Fusion-Associated Sarcomas
Sammanfattning : .... LÄS MER
25. Tumor-associated macrophages and microglia : double-edged sword in tumor evolvement and invasion
Sammanfattning : Tumor-associated macrophages (TAMs) are among the most abundant cell types in the tumor microenvironment. TAM infiltration is usually linked to tumor progression, metastasis and poor clinical outcome in most human cancers. LÄS MER
