Sökning: "Tumor detection"

Visar resultat 6 - 10 av 216 avhandlingar innehållade orden Tumor detection.

  1. 6. Genetic Analyses of Tumor Progression in Colorectal Cancer

    Författare :Kristina Lagerstedt; Göteborgs universitet; []
    Nyckelord :colorectal cancer; tumor progression; microarray; DNA aberration; gene expression; microRNA; structural variation;

    Sammanfattning : Colorectal tumors are responsible for more than 600 000 deaths per year worldwide and thereby constitute the second most common cause of cancer related mortality. Early detection is related to improved prognosis and identification of genetic biomarkers would meliorate available diagnostic tools. LÄS MER

  2. 7. Nuclease Activity as a Biomarker in Cancer Detection

    Författare :Alien Balian; Frank Hernandez; Kajsa Uvdal; Baris Ata Borsa; Ester Boix Borrás; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nucleases; Nuclease activity; Cancer detection; Diagnosis; Oligonucleotides; Nucleic acid probes; MRI-probes; Activatable probes;

    Sammanfattning : Nucleases are a group of enzymes that cleave the phosphodiester bonds in nucleic acids. As such, nucleases act as biological scissors that exhibit a plethora of fundamental roles, in prokaryotes and eukaryotes, dependent or non-dependent on their catalytic capability. LÄS MER

  3. 8. Pancreatic Cancer - Early Detection, Prognostic Factors, and Treatment

    Författare :Daniel Ansari; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; artificial neural networks; apicidin; centralization; early detection; epigenetics; high definition mass spectrometry; MUC4; pancreatic cancer; pancreaticoduodenectomy; prognostic factors; xenograft model; treatment;

    Sammanfattning : Background: Pancreatic cancer is the fourth leading cause of cancer-related death. Only about 6% of patients are alive 5 years after diagnosis. One reason for this low survival rate is that most patients are diagnosed at a late stage, when the tumor has spread to surrounding tissues or distant organs. LÄS MER

  4. 9. Deep learning algorithms for tumor detection in screening mammography

    Författare :Mattie Salim; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Population-wide mammography screening was fully implemented in Sweden in 1997. The implementation has helped to identify breast cancer at earlier stages and thereby lowered mortality by 30-40%. However, it still has its limitations, many studies have shown a discrepancy between radiologist when assessing mammographic examinations. LÄS MER

  5. 10. Molecular Tools for Biomarker Detection

    Författare :Lei Chen; Ulf Landegren; Niko Hildebrandt; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Rolling circle amplification; padlock probe;

    Sammanfattning : The advance of biological research promotes the emerging of new methods and solutions to answer the biological questions. This thesis describes several new molecular tools and their applications for the detection of genomic and proteomic information with extremely high sensitivity and specificity or simplify such detection procedures without compromising the performance. LÄS MER