Sökning: "Tumor Necrosis Factor alpha"

Visar resultat 6 - 10 av 89 avhandlingar innehållade orden Tumor Necrosis Factor alpha.

1. 6. Platelet-activating factor, intestinal epithelial cells, and Chron's disease : An experimental study

   Författare :Bengt Kald; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Platelet-activating factor (PAF-acethcr, 1-0-alky l-2-acetyl-s n- glycero-3- phosphocholine), is a potent inflammatory mediator that can be formed by a variety of cells and tissues. In the present investigation, the content of PAFacether was determined in mucosal biopsies from the ileum and colon of patients with Crohn's disease and control patients. LÄS MER

3. 7. Angiogenesis in childhood malignancies

   Författare :Erik Sköldenberg; Rolf Christofferson; Göran Läckgren; Agneta Nordenskjöld; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Angiogenesis Factor; Biopsy; Needle; Neovascularization; Pathologic; Nephroblastoma; Reference value; Kirurgi; Surgery; Kirurgi; Pediatric Surgery; kirurgi; särskilt barnkirurgi;

   Sammanfattning : Angiogenesis is necessary for the growth and spread of solid tumors. In these studies angiogenesis was measured in childhood malignancies in general and in Wilms’ tumor in particular, and cutting needle biopsy (CNB) specimens were evaluated for diagnosis in childhood renal tumors. LÄS MER

4. 8. An albumin-binding domain as a scaffold for bispecific affinity proteins

   Författare :Johan Nilvebrant; Sophia Hober; Andrew Bradbury; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; albumin-binding domain; bispecific; albumin; affinity protein; phage display; staphylococcal display; orthogonal affinity purification; TNF-alpha; ErbB2; ErbB3; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

   Sammanfattning : Protein engineering and in vitro selection systems are powerful methods to generate binding proteins. In nature, antibodies are the primary affinity proteins and their usefulness has led to a widespread use both in basic and applied research. LÄS MER

5. 9. Inflammation and ischemia in the developing brain - modifying effects of hyperoxia and adrenoceptor activation

   Författare :Tina Markus; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adrenergic; preconditioning; excitotoxicity; tissue culture; hyperoxia; resuscitation; asphyxia; sensitization; TNF-alpha; inflammatory mediators; hippocampus; neonate;

   Sammanfattning : Inflammation and ischemia are common causes of perinatal brain damage. Ventilation with pure oxygen has previously been the prime choice during resuscitation following fetal asphyxia. LÄS MER

7. 10. Calcium metabolism and cytokines in critical illness

   Författare :Fredrik Carlstedt; Uppsala universitet; []
   Nyckelord :Medical sciences; calcium; critical illness; hemodynamics; hypocalcemia; IL-6; mortality; TNF-alpha; severity of disease; sepsis; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : Hypocalcemia is a common finding in critically ill patients, particularly in those with sepsis, and has been found to be associated with increased mortality. The pathogenesis of this altered calcium metabolism is unknown and the effects of calcium supplementation are poorly investigated. LÄS MER