Sökning: "Troels Skrydstrup"

Hittade 4 avhandlingar innehållade orden Troels Skrydstrup.

  1. 1. Radical Cyclization Approaches to Pyrrolidines

    Författare :Magnus Beşev; Troels Skrydstrup; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Radical cyclization; diastereselectivity; pyrrolidine; pyrroline; thiazoline; aziridine; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : Five-membered rings are readily prepared by 5-exo-trig radical cyclization. This thesis is concerned with novel methodology for pyrrolidine synthesis. We have synthesised selenium containing radical precursors from aziridines and α-phenylseleno ketones, and cyclized them to 2,4- and 3,4-disubstituted pyrrolidines. LÄS MER

  3. 2. Novel Metal-Mediated Organic Transformations : Focusing on Microwave Acceleration and the Oxidative Heck Reaction

    Författare :Per-Anders Enquist; Mats Larhed; Anders Hallberg; Troels Skrydstrup; Uppsala universitet; []
    Nyckelord :Organic chemistry; palladium II ; oxidative Heck reaction; high-throughput-chemistry; microwave acceleration; dicobalt octacarbonyl; in situ carbonylation; urea; diaryl ketones; ESI-MS; Organisk kemi;

    Sammanfattning : Transition metals have played an important role in synthetic organic chemistry for more than a century, and offer catalytic transformations that would have been impossible with classical chemistry. One of the most useful and versatile of the transition metals is palladium, which over the years has catalyzed many important carbon-carbon forming reactions. LÄS MER

  4. 3. Exploring Novel Catalytic Chalcogenide Antioxidants

    Författare :Henrik Johansson; Lars Engman; Helena Grennberg; Troels Skrydstrup; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; antioxidant; tellurium; selenium; catalytic; toxicity; ROS; neutrophil; glutathione peroxidase mimic; macrophage.; Organic chemistry; Organisk kemi; Kemi med inriktning mot organisk kemi; Chemistry with specialization in Organic Chemistry;

    Sammanfattning : This thesis is concerned with the synthesis and evaluation of regenerable chalcogen containing antioxidants. Variously substituted 2,3-dihydrobenzo[b]selenophene-5-ol antioxidants were evaluated in order to gain information about structure/reactivity-relationships. LÄS MER

  5. 4. Advances in Stereoselective Palladium(ΙΙ)-Catalyzed Oxidative Transformations of Allenes

    Författare :Daniels Posevins; Jan-Erling Bäckvall; Troels Skrydstrup; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Synthesis; Palladium Catalysis; Allenes; Biomimetic; Carbocyclization; Borylation; Carbonylation; Oxidation; Heterogeneous; organisk kemi; Organic Chemistry;

    Sammanfattning : Palladium(ΙΙ)-catalyzed carbon-carbon and carbon-heteroatom bond formation via selective C-H bond oxidation constitutes a step-economical and versatile approach towards complex target molecules. This thesis has been focused on the development of new selective palladium(ΙΙ)-catalyzed transformations of allenes under oxidative conditions catalyzed by either homogenous or heterogeneous palladium(ΙΙ) catalysts. LÄS MER