Sökning: "Transcriptomics Spatial"

Visar resultat 6 - 10 av 40 avhandlingar innehållade orden Transcriptomics Spatial.

  1. 6. Spatially resolved and single cell transcriptomics

    Författare :Fredrik Salmén; Joakim Lundeberg; Patrik Ståhl; Elaine R. Mardis; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; spatial; transcriptomics; single cell; 3D; RNA-sequencing; Bioteknologi; Biotechnology;

    Sammanfattning : In recent years, massive parallel sequencing has revolutionized the field of biology and has provided us with a vast number of new discoveries in fields such as neurology, developmental biology and cancer research. A significant area is deciphering gene expression patterns, as well as other aspects of transcriptome information, such as the impact of splice variants and mutations on biological functions and disease development. LÄS MER

  3. 7. Development and application of spatial transcriptomics methods

    Författare :Zaneta Andrusivova; Joakim Lundeberg; Jay W. Shin; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA; Spatial Transcriptomics; RNA sequencing; Biotechnology; Bioteknologi;

    Sammanfattning : Transcriptomics is one of the pivotal fields in molecular biology, enabling comprehensive analysis of gene expression patterns. Recent advancements in the biotechnology field have transformed the transcriptomics research, providing insights into the complexity of cellular processes in a greater detail. LÄS MER

  4. 8. Mapping Transcriptomes in Tissues

    Författare :Ludvig Larsson; Joakim Lundeberg; Stefania Giacomello; Naveed Ishaque; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; spatially resolved transcriptomics; spatial transcriptomics; transcriptomics; data analysis; rumsligt upplöst transkriptomik; rumslig transkriptomik; transkriptomik; dataanalys; Biotechnology; Bioteknologi;

    Sammanfattning : Over the past few decades, the advent of pioneering biotechnological methods has allowed scientists to analyze the molecular components of multicellular organisms with remarkable precision. The field of transcriptomics has witnessed a rapid development of technologies for gene expression profiling of biological samples. LÄS MER

  5. 9. Spatial Tissue Mapping on Joint Biopsies from Arthritis Patients

    Författare :Konstantin Carlberg; Patrik Ståhl; Vivianne Malmström; Anna-Karin Hultgård Ekwall; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immune prediction; Rheumatoid arthritis; Spatial RIN; Spatial Transcriptomics; Spondyloarthritis; Bioteknologi; Biotechnology;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that mainly affects joints, causing discomfort and pain that severely reduces the life quality of affected individuals. Its etiology is largely unknown, but some pathophysiological mechanisms have been identified. LÄS MER

  7. 10. Spatially Resolved Gene Expression Analysis

    Författare :Michaela Asp; Joakim Lundeberg; Patrik Ståhl; Thierry Voet; KTH; []
    Nyckelord :RNA; RNA-sequencing; transcriptomics; spatial transcriptomics; single cells; Bioteknologi; Biotechnology;

    Sammanfattning : Spatially resolved transcriptomics has greatly expanded our knowledge of complex multicellular biological systems. To date, several technologies have been developed that combine gene expression data with information about its spatial tissue context. LÄS MER