Sökning: "Transcriptome"

Visar resultat 6 - 10 av 327 avhandlingar innehållade ordet Transcriptome.

  1. 6. Genome and Transcriptome Comparisons between Human and Chimpanzee

    Författare :Anna Wetterbom; Ulf Gyllensten; Lucia Cavelier; Tomas Bergström; Evan Eichler; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; chimpanzee; genome; transcriptome; comparative studies; exon arrays; next-generation sequencing; premature termination codon; alternative splicing; primate evolution; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Bioinformatik; Bioinformatics;

    Sammanfattning : The chimpanzee is humankind’s closest living relative and the two species diverged ~6 million years ago. Comparative studies of the human and chimpanzee genomes and transcriptomes are of great interest to understand the molecular mechanisms of speciation and the development of species-specific traits. LÄS MER

  3. 7. Methylome and Transcriptome Profiling of Hepatocytes Derived from Human Pluripotent Stem Cells

    Författare :Nidal Ghosheh; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human pluripotent stem cells; gene transcription; gene regulation; DNA methylation; transcriptome; hepatocytes;

    Sammanfattning : Six hundred million people suffering from liver diseases worldwide of which the lethality is two million. Freshly isolated hepatocytes from the liver have been used for transplantation purposes and are extensively used to recapitulate drug metabolism. LÄS MER

  4. 8. Endocrine disruption in fish : Effects of 17α-ethinylestradiol exposure on non-reproductive behavior, fertility and brain and testis transcriptome

    Författare :Tove Porseryd; Inger Porsch Hällström; Ioanna Katsiadaki; Södertörns högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 17α-ethinylestradiol; endocrine disrupting chemical; fish; behavior; fertility; transcriptome; RNA sequencing; Environmental Studies; Miljövetenskapliga studier; Östersjö- och Östeuropaforskning; Baltic and East European studies;

    Sammanfattning : Aquatic environments are the end recipient for most anthropogenic chemical pollutants. One common chemical pollutant found in the aquatic environment is 17α-ethinylestradiol (EE2), a synthetic estrogen used in contraceptive pills. LÄS MER

  5. 9. Transcriptome Analyses of the Nematode-trapping Fungus Monacrosporium haptotylum

    Författare :Margareta Tholander; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Biologi; Microbiology; bacteriology; virology; mycology; Pathogenic fungi; Nematophagous fungi; Nematodes; Biological control; cDNA microarray; Transcriptome analysis; Nematode-trapping fungi; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Nematode-trapping fungi are soil living organisms with the ability to infect and kill nematodes. These fungi have developed specialized infection structures, traps for the capture of nematodes. To be able to identify genes in nematode-trapping fungi that are involved in the infection of nematodes cDNA microarrays were constructed. LÄS MER

  7. 10. Development and Application of Genomic Resources in Non-model Bird Species

    Författare :Biao Wang; Jacob Höglund; Christopher Wheat; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; genome; transcriptome; next generation sequencing; non-model species; bioinformatics; reference guided assembly; RNA-Seq; comparative genomics; gene expression; major histocompatibility complex; single nucleotide polymorphism; microsatellite; Biologi; Biology;

    Sammanfattning : Understanding the genetic basis of biological processes is a fundamental component of modern ecology and evolutionary biology studies. With the recent advent of next generation sequencing (NGS) technologies, it is now possible to perform large genome and transcriptome projects for ecologically important non-model species. LÄS MER