Sökning: "Transcription"

Visar resultat 16 - 20 av 1971 avhandlingar innehållade ordet Transcription.

1. 16. Functional collaboration between HLH transcription factors in B cell development

   Författare :Ramiro Gisler; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; E47; Early B cell Factor EBF ; Clinical genetics; Klinisk genetik; HLH proteins; transcription factors; gene expression; B cell development; transcription regulation;

   Sammanfattning : The cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. LÄS MER

3. 17. The hematopoietic transcription factor RUNX1 : a structural view

   Författare :Stefan Bäckström; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; RUNX1; Runt domain; CBFβ; transcription factor; leukaemia; protein crystallography; anomalous diffraction; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; molekylärbiologi; Molecular Biology;

   Sammanfattning : The malfunction of the transcriptional regulator RUNX1 is the major cause of several variants of acute human leukemias and its normal function is to regulate the development of the blood system in concert with other transcriptional co-regulators. RUNX1 belongs to a conserved family of heterodimeric transcription factors that share a conserved DNA binding domain, the Runt domain (RD), named after the first member of this group – Runt - found in Drosophila melanogaster. LÄS MER

4. 18. Factors regulating transcription and translation of the mammalian mitochondrial genome

   Författare :Ann Mutvei; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : .... LÄS MER

5. 19. Functional Characterization of the Cellular Protein p32 : A Protein Regulating Adenovirus Transcription and Splicing Through Targeting of Phosphorylation

   Författare :Christina Öhrmalm; Göran Akusjärvi; Neus Visa; Uppsala universitet; []
   Nyckelord :Cell and molecular biology; Adenovirus; p32; ASF SF2; E4-ORF4; Splicing; Transcription; CTD; RNA Pol II; Cell- och molekylärbiologi;

   Sammanfattning : Cellular processes involved in the conversion of the genetic information from DNA into a protein are often regulated by reversible phosphorylation reactions. By modulating the phosphorylated status of key proteins their activity can either be enhanced or repressed. LÄS MER

7. 20. Calcium regulation and functions of basic Helix-Loop-Helix transcription factors

   Författare :Juha Saarikettu; Thomas Grundström; Dan Holmberg; Mikael Sigvardsson; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; calcium; calmodulin; calretinin; transcription; bHLH; E-protein; E2-2; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

   Sammanfattning : The members of the ubiquitously expressed E-protein subfamily of basic Helix-Loop-Helix (bHLH) transcription factors, E12/E47, SEF2-1 and HEB, have important roles as regulators of gene expression in various differentiation processes, including lymphocyte development and myogenesis. In myogenesis, E-proteins are proposed to function as obligate heterodimer partners for members of the MyoD family of muscle-specific bHLH transcription factors. LÄS MER