Sökning: "Transcription termination"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden Transcription termination.

  1. 1. Regulation of Human Mitochondrial DNA Replication and Transcription

    Författare :Majda Mehmedovic; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mitochondria; mtDNA; replication; transcription; TFAM;

    Sammanfattning : Mitochondria are organelles in eukaryotic cells, which through oxidative phosphorylation (OXPHOS) produce most of the ATP used to drive cellular processes. The organelle contains its own genetic material, mitochondrial DNA (mtDNA), which encodes 13 key components of the OXPHOS machinery. LÄS MER

  3. 2. Unraveling the regulatory mechanisms of pupal diapause termination

    Författare :Philip Süess; Philipp Lehmann; Christian Wegener; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Diapause; diapause termination; prothoracicotropic hormone; ecdysone; thermal performance; Functional Zoomorphology; funktionell zoomorfologi;

    Sammanfattning : Diapause is an essential part of many insect’s life cycle and is a developmental halt induced by environmental cues in advance of deteriorating conditions. Insects typically enter diapause to avoid unfavorable environmental conditions like low temperatures, poor food quality and the absence of conspecifics. LÄS MER

  4. 3. Mediator and its role in non-coding RNA and chromatin regualtion

    Författare :Jonas O P Carlsten; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mediator; transcription; centromere; telomere; tRNA; exosome;

    Sammanfattning : Mediator is a multiprotein complex required for the regulation of RNA Polymerase II (Pol II) transcription. Mediator transmits regulatory signals from activators and repressors to the Pol II machinery at the promoter, but the complex has also many other functions related to control of gene transcription. LÄS MER

  5. 4. Regulation of TGF-β Signaling by Post-Translational Modifications

    Författare :Peter Lönn; Aristidis Moustakas; Carl-Henrik Heldin; Petra Knaus; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TGF-β; Smad; PARP-1; PARG; ALK5; SIK; signal transduction; transcription; post-translational modification; phosphorylation; ubiquitin; ADP-ribosylation; DNA-binding; receptor degradation; Cell and molecular biology; Cell- och molekylärbiologi; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Sammanfattning : Transforming growth factor-β (TGF-β) signaling is initiated when the ligand binds to type II and type I serine/threonine kinase receptors at the cell surface. Activated TGF-β type I receptors phosphorylate R-Smads which relocate, together with co-Smads, to the cell nucleus and regulate transcription. LÄS MER

  7. 5. Transcription kinetics in pluripotent cells : RNA turnover, transcription velocity, and epigenomic regulation

    Författare :Rui Shao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Transcriptional regulation is one of the primary steps in gene expression control. It is now appreciated that a large fraction of coding genome is transcribed in concert of other functional RNAs. LÄS MER