Sökning: "Topology"

Visar resultat 6 - 10 av 581 avhandlingar innehållade ordet Topology.

1. 6. Dual-topology membrane proteins in Escherichia coli

   Författare :Susanna Seppälä; Gunnar von Heijne; Dirk Jan Slotboom; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; membrane protein topology; dual-topology; evolution; Escherichia coli; Biochemistry; biokemi;

   Sammanfattning : Cellular life, as we know it, is absolutely dependent on biological membranes; remarkable superstructures made of lipids and proteins. For example, all living cells are surrounded by at least one membrane that protects the cell and holds it together. LÄS MER

3. 7. Topology optimization of vehicle structures

   Författare :Torbjörn Johansen; Linköpings universitet; []
   Nyckelord :topology optimization; frame structure; vehicle structure; flexible joint; TECHNOLOGY; TEKNIKVETENSKAP;

   Sammanfattning : This thesis concerns topology optimization of vehicle structures. Vehicle structures are considered to be composed of beams joined together and the work has been focused on a method for beam topology optimization including joints. LÄS MER

4. 8. Topology optimization of transitional flows

   Författare :Harrison Nobis; Dan Henningson; Philipp Schlatter; Paolo Luchini; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Direct Numerical Simulation; Topology Optimization; Laminar– Turbulent Transition; Spectral Element Method; Direkt numerisk simulering; topologioptimering; laminär–turbulent omslag; spektralelementmetod; Teknisk mekanik; Engineering Mechanics;

   Sammanfattning : This thesis is concerned with the application of topology optimization in thedesign of structures that control fluids. A framework is developed in the high-order Spectral Element Method (SEM) code Nek5000, extending Nek5000 fromits original capabilities, performing Direct Numerical Simulations (DNS), toperforming density-based topology optimization. LÄS MER

5. 9. The birth and growth of the protein folding nucleus : Studies of protein folding focused on critical contacts, topology and ionic interactions

   Författare :Linda Hedberg; Mikael Oliveberg; Christopher Johnson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein folding; protein stability; two-state folding; chevron plot; transition-state movements; Hammond behaviour; topology; electrostatic interactions; pH dependence; mass-action; protein engineering; pKa; Biochemistry; Biokemi; biokemi; Biochemistry;

   Sammanfattning : Proteins are among the most complex molecules in the cell and they play a major role in life itself. The complexity is not restricted to just structure and function, but also embraces the protein folding reaction. LÄS MER

7. 10. GFP as a tool to monitor membrane protein topology and overexpression in Escherichia coli

   Författare :David Drew; Jan-Willem de Gier; Gunnar von Heijne; Bert Poolman; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; GFP; membrane protein; topology; overexpression; high-throughput; Biochemistry; Biokemi;

   Sammanfattning : Membrane proteins are essential for life, and roughly one-quarter of all open reading frames in sequenced genomes code for membrane proteins. Unfortunately, our understanding of membrane proteins lags behind that of soluble proteins, and is best reflected by the fact that only 0. LÄS MER