Avancerad sökning

Hittade 5 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Platelets in inflammation : Role of complement protein C1q, C-reactive proteinand toll-like receptors

   Författare :Caroline Skoglund; Torbjörn Bengtsson; Jonas Wetterö; Pentti Tengvall; David Erlinge; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Platelets are proven essential in haemostasis, however, they are now also increasingly recognized as cells with important immunomodulatory properties, e.g. through interaction with leukocytes and several species of bacteria and by release inflammatory mediators upon activation. LÄS MER

3. 2. Preterm and term cervical ripening : studies on CRH, HMGB1, toll-like receptors, cytokines and matrix metalloproteinases

   Författare :Aurelija Dubicke; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cervical fibroblasts; cervical ripening; cervix; chemokines; cytokines; CRH; HMGB1; interleukin; labor; preterm; preterm labor; matrix metalloproteinases; pregnancy; PPROM; Tolllike receptors;

   Sammanfattning : Objective: Preterm birth (PTB) is the leading cause of neonatal mortality and morbidity. Despite the existing treatment, the frequency of PTB has not changed in the past thirty years. Incomplete understanding of the biological and pathophysiological mechanisms underlying preterm delivery is the major obstacle to preventing PTB. LÄS MER

4. 3. Bridging innate and adaptive immunity in cardiovascular disease

   Författare :Glykeria Karadimou; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Cardiovascular disease is the leading cause of death and morbidity in the world. Myocardial infarction and stroke constitute the main manifestations of atherosclerosis that lead to the majority of cardiovascular events. Calcific aortic valve stenosis is the most common valve pathology. LÄS MER

5. 4. Glycan-based interactions of Streptococcus pneumoniae and the host

   Författare :Karina Hentrich; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Streptococcus pneumoniae is commonly found as an asymptomatic colonizer of the nasopharynx of children, but it can also translocate to normally sterile body sites and cause severe diseases, like pneumonia, septicemia or meningitis. Pneumococci spread via aerosols. LÄS MER

7. 5. Studies on immunological mechanisms of induced arthritis in the rat

   Författare :Lena Svelander; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Arthritis; autoimmunity; adjuvant; incomplete Freund s adjuvant; squalene; CpG;

   Sammanfattning : Experimental arthritis induced with adjuvants shares many features with the human autoimmune disorder rheumatoid arthritis (RA). The use of arthritis models is therefore a relevant approach in the search for pathogenic mechanisms in human disease. LÄS MER