Sökning: "Toll-like receptor 4"

Visar resultat 21 - 25 av 48 avhandlingar innehållade orden Toll-like receptor 4.

  1. 21. Tuberculosis - Clinical Value of Initial Host Molecular Signalling and Molecular Fingerprinting

    Detta är en avhandling från Lund University: Faculty of Medicine

    Författare :Nader Alaridah; Lund University.; Lunds universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Mycobacterium tuberculosis (Mtb) is principally a pulmonary pathogen infecting one-third of the world's population and causing two million deaths annually. The only approved tuberculosis vaccine today is the Mycobacterium bovis bacilli Calmette-Guérin (BCG). LÄS MER

  2. 22. Regulation of dendritic cell differentiation, maturation and activation

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Medicine, Solna

    Författare :Jin Hu; Karolinska Institutet.; Karolinska Institutet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The human immune system efficiently protects the host from exogenous pathogens such as bacteria, virus and parasites and endogenous threats such as damaged cells and tumors. Invasion of pathogens and other threats activate the innate immunity causing secretion of pro-inflammatory cytokines with the subsequent antigen presentation and activation of the adaptive immunity resulting in T and B cell responses. LÄS MER

  3. 23. Compartmentalisation of the immune response in human skin : cross-talk between dendritic cells and T cells in healthy conditions and in psoriasis

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Medicine, Solna

    Författare :Elisa Martini; Karolinska Institutet.; Karolinska Institutet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Human skin is highly compartmentalised and distinct subsets of dendritic cells (DCs) and T cells reside in epidermis and dermis. Alterations in the composition of DCs and T cells have been observed in psoriasis, a common cytokine-driven focal inflammatory skin disease. LÄS MER

  4. 24. Immune modulation of macrophages by the meningococcal surface protein NhhA

    Detta är en avhandling från Stockholm : Stockholm University

    Författare :Xiao Wang; Stockholms universitet.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Functional immune modulation of macrophages play important role during bacterial infection. Neisseria meningitidis, a gram-negative diplococcal bacterium, is the leading cause of bacterial meningitis and fatal septic shock. However, it is also a commensal bacterium that colonizes the nasopharynx of healthy individuals asymptomatically. LÄS MER

  5. 25. Regulation of human immune responses to allergens

    Detta är en avhandling från Göteborg : Göteborg University

    Författare :Anna-Carin Lundell; Göteborgs universitet.; Gothenburg University.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; recognition receptors; antigen-presenting cells; sCD14; sCD83; T cells; neonates; gut microflora; staphylococcus aureus; allergens; allergy; children;

    Sammanfattning : The incidence of allergic diseases is increasing in the industrialized countries. Epidemiological studies indicate that there is an association between exposure to high levels of endotoxin or cat allergen during infancy and reduced risk of developing allergic diseases later in childhood. LÄS MER