Sökning: "Toll-like receptor 4"

Visar resultat 21 - 25 av 52 avhandlingar innehållade orden Toll-like receptor 4.

  1. 21. Pattern-recognition receptors and neutrophils in cancer inflammation

    Författare :Camilla Rydberg Millrud; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic inflammation, induced by the use of tobacco and alcohol, or caused by infections has long been suggested to constitute a risk factor for head and neck squamous cell carcinoma (HNSCC). The innate immunity is the first line of defense against pathogens, comprising physical and chemical barriers, anti-microbial peptides, pattern-recognition receptors (PRRs) as well as different kinds of cells, including neutrophils. LÄS MER

  3. 22. Signaling and Adhesive Mechanisms in Acute Pancreatitis

    Författare :Darbaz Awla; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; trypsinogen activation; Acute pancreatitis; leukocyte recruitment and adhesion;

    Sammanfattning : Acute pancreatitis (AP) is an inflammatory disease with variable severity ranging from mild interstitial edematous to severe necrotizing disease. The overall mortality rate of AP is 8-9%. Specific treatment of AP is lacking which is partly related to an incomplete understanding of the basic pathophysiology behind the disease. LÄS MER

  4. 23. Modulation of cellular innate immune responses by lactobacilli

    Författare :Mattias Karlsson; Jana Jass; Robert Brummer; Gilbert Donders; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytokines; immunomodulation; lactobacilli; probiotics; urinary tract infections; urothelium; Biology; Biologi;

    Sammanfattning : Lactobacillus is a genus of lactic acid bacteria frequently used as healthpromoting probiotics. Using probiotics to treat or prevent infections is a novel experimental approach with vast impact on future therapy. LÄS MER

  5. 24. Tuberculosis - Clinical Value of Initial Host Molecular Signalling and Molecular Fingerprinting

    Författare :Nader Alaridah; Malmö Medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Mycobacterium tuberculosis (Mtb) is principally a pulmonary pathogen infecting one-third of the world's population and causing two million deaths annually. The only approved tuberculosis vaccine today is the Mycobacterium bovis bacilli Calmette-Guérin (BCG). LÄS MER

  7. 25. Regulation of dendritic cell differentiation, maturation and activation

    Författare :Jin Hu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The human immune system efficiently protects the host from exogenous pathogens such as bacteria, virus and parasites and endogenous threats such as damaged cells and tumors. Invasion of pathogens and other threats activate the innate immunity causing secretion of pro-inflammatory cytokines with the subsequent antigen presentation and activation of the adaptive immunity resulting in T and B cell responses. LÄS MER