Sökning: "Toll-like receptor 4"

Visar resultat 16 - 20 av 52 avhandlingar innehållade orden Toll-like receptor 4.

  1. 16. Characterization of host and microbe interactions affecting adherence, clearance and systemic spread of S. pneumoniae

    Författare :Sofia Dahlberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Streptococcus pneumoniae (the pneumococcus) mainly gives rise to diseases of the respiratory tract, such as pneumonia, acute otitis media and sinusitis, but it also causes severe invasive diseases, such as meningitis and sepsis. The pneumococcus accounts for approximately two million deaths world-wide every year, the majority of which are children in developing countries. LÄS MER

  3. 17. Pattern-recognition receptors in airway inflammation

    Författare :Anna-Karin Ekman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Airway inflammation is a defining feature of allergic rhinitis and asthma. Bacterial and viral infections are known to cause exacerbations of both diseases, but knowledge about the mechanisms involved is limited. LÄS MER

  4. 18. Experimental Chagas disease

    Författare :John Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Trypanosoma cruzi; NK cells; cytotoxicity; IFN-gamma; IL-12; IFN-alpha beta; Chagas disease; polymyositis; myocarditis; genotype dependence and Toll-like receptors.;

    Sammanfattning : The main focus of this thesis was to develop and utilise experimental models using the protozoan parasite Trypanosoma cruzi. We were especially interested in studying the activation of NK cells early after T. cruzi infection and what factors that predispose to a chronic inflammatory disease after T. cruzi infection. LÄS MER

  5. 19. Alternative feed sources : Effect on gut microbiota, immunity and health of rainbow trout

    Författare :Aprajita Aprajita; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Shifting from conventional fishmeal- and soymeal-based aquafeed to low-cost, sustainable dietary alternatives is essential for expansion and resilience in aquaculture. Possible alternative feed resources include under-utilised organic wastes from agriculture and households and by-products from forestry. LÄS MER

  7. 20. Macrophage programming and host responses to bacterial infection

    Författare :Xiao Wang; Hong Sjölinder; Martin Rottenberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Macrophages; meningococci; mycobacteria; NhhA; CD46; cytokines; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Macrophages are dynamic, plastic, and heterogeneous immune cells that play an important role in host immune defense against bacterial infection. Various bacterial pathogens, such as Neisseria meningitidis and Mycobacterium tuberculosis, can modulate host immune responses by interfering with macrophage differentiation and polarization. LÄS MER