Sökning: "Tina Kunz"

Hittade 1 avhandling innehållade orden Tina Kunz.

1. 1. The Role of Cyclooxygenase-2 in Models of Epilepsy and Traumatic Brain Injury : Effects of Selective Cyclooxygenase-2 Inhibitors

   Författare :Tina Kunz; Tadeusz Wieloch; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Controlled cortical contusion injury; fluid percussion injury; limbic seizures; nuclear factor-kappa B; prostaglandin metabolism; TUNEL staining; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

   Sammanfattning : Cyclooxygenase-2 (COX-2) catalyses prostaglandin synthesis from arachidonic acid during inflammation. COX-2 is expressed in the normal brain and is induced in neurological disorders. There is evidence that COX-2 is involved in secondary events leading to cell death in the brain. LÄS MER