Sökning: "Thysell"

Hittade 4 avhandlingar innehållade ordet Thysell.

1. 1. Multivariate profiling of metabolites in human disease : Method evaluation and application to prostate cancer

   Författare :Elin Thysell; Henrik Antti; Janne Lehtiö; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolite profiling; metabolomics; predictive metabolomics; mass spectrometry; GC-MS; biomarkers; chemometrics; design of experiments; multivariate data analysis; prostate cancer; bone metastases; plasma; biologisk kemi; biological chemistry;

   Sammanfattning : There is an ever increasing need of new technologies for identification of molecular markers for early diagnosis of fatal diseases to allow efficient treatment. In addition, there is great value in finding patterns of metabolites, proteins or genes altered in relation to specific disease conditions to gain a deeper understanding of the underlying mechanisms of disease development. LÄS MER

3. 2. MicroRNA expression profiles in prostate cancer bone metastases : functional effects of microRNA-23c, -375, and -4328

   Författare :Helena Järemo; Pernilla Wikström; Maria Brattsand; Anders Bergh; Elin Thysell; Guido Jenster; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer bone metastases; microRNA; metastatic subtypes; extracellular vesicles; Pathology; patologi;

   Sammanfattning : Non-coding microRNAs (miRNAs) function as post-transcriptional regulators of gene expression by interacting with messenger RNA. Dysregulation of miRNAs has many possible consequences, including tumor-suppressive or -promoting ones, and restoring or preventing the effects of miRNA alteration has therapeutic potential. LÄS MER

4. 3. Clinical and morphological aspects of metastatic spinal cord compression

   Författare :Johan Wänman; Sead Crnalic; Lukas Bobinski; Pawel Grabowski; Pernilla Wikström; Anders Bergh; Elin Thysell; Helena Brisby; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bone metastasis; metastatic spinal cord compression; surgery for spinal metastases; Spinal Instability Neoplastic Score; prostate cancer; Orthopaedics; ortopedi; Orthopaedics; ortopedi;

   Sammanfattning : Background: Metastatic spinal cord compression (MSCC) is a serious complication of cancer leading to demyelination and axonal damage of the spinal cord with a risk of para/tetraplegia. It is most common in patients with known cancer but may also be the initial manifestation of malignancy (IMM). LÄS MER

5. 4. I den goda vårdens namn : Sinnesslövård i 1950-talets Sverige

   Författare :Sara Hansson; John Rogers; Mattias Tydén; Uppsala universitet; []
   Nyckelord :History; feeble-minded; mental deficiency; IQ-testing; differentiation; institutional care; modernity; rationality; pedagogy; psychology; experts; Sweden; 1950s; welfare state; social engineering; Slagsta; Hans Forssman; Torsten Thysell; mass media; National Medical Board; individualization; Historia;

   Sammanfattning : In 1952 the Swedish parliament commissioned a total evaluation of 13,000 institutionalized individuals designated in the terminology of the day as feeble-minded. The evaluation provides a unique opportunity to attain new knowledge about how the system of institutionalized care of the feeble-minded developed, functioned and was eventually transformed. LÄS MER