Sökning: "Thyroid hormone receptors"

Visar resultat 1 - 5 av 37 avhandlingar innehållade orden Thyroid hormone receptors.

  1. 1. Life without thyroid hormone receptors

    Författare :Sten Göthe; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Thyroid hormone (TH) has many important functions during development and in the adult individual. It reaches its target cells via the blood system and binds its receptor (TR) located within the cell nucleus where the receptor regulates target genes. This hormone-mediated gene regulation is a finely tuned interplay of numerous parameters. LÄS MER

  3. 2. Thyroid hormone receptors in liver metabolism

    Författare :Hjalmar Gullberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Thyroid hormone has a profound impact on mammalian metabolism; hypothyroidism causes decreased metabolic rate and increased serum cholesterol levels. One major target organ for the hormone is the liver, the most important metabolic organ in mammals, that balances anabolism of carbohydrates and lipids against catabolism. LÄS MER

  4. 3. Regulation of gene transcription by the thyroid hormone receptors

    Författare :Maria Nygård; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Thyroid hormone receptors; T3; cell differentiation; gene regulation; E2F-1; Necdin; TRH; nTRE; RXR; NCoR; XAP-2;

    Sammanfattning : Thyroid hormone (TH) has important effects on postnatal development as well as on adult metabolic homeostasis. TH meditates its effects through different isoforms of the thyroid hormone receptors (TRs) encoded by the TRalpha and TRbeta genes, respectively. TRs belong to the nuclear hormone receptor superfamily. LÄS MER

  5. 4. Thyroid hormone receptors and the regulation of bone physiology

    Författare :Jenny Kindblom; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : The aim of the studies in this thesis was to investigate the role of thyroid hormone receptors in bone physiology. Thyroid hormone signals through its receptors, the TRs, and has profound effects on bone development and metabolism, as demonstrated in hypo- and hyperthyroidism. LÄS MER

  7. 5. Temporal dynamics of brain and hormone changes during parr-smolt transformation in salmon

    Författare :Lars Ebbesson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; animal morphology; Animal anatomy; growth hormone; metamorphosis; thyroid hormones; neural plasticity; Djurs anatomi och morfologi;

    Sammanfattning : This thesis describes a series of studies designed to elucidate brain circuitry changes during parr-smolt transformation (smoltification) in salmon. The studies revealed sequential orderly chemical and structural changes of the brain. LÄS MER