Sökning: "Thyroid cancer"

Visar resultat 1 - 5 av 65 avhandlingar innehållade orden Thyroid cancer.

  1. 1. Thyroid cancer : studies on etiology and prognosis

    Författare :Arne Hallquist; Lennart Hardell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thyroid cancer; prognostic factors; etiology; occupation; medical ionizing radiation; reproductive; and family factors;

    Sammanfattning : Thyroid cancer constitutes about 1% of all malignant tumours and the incidence is increasing in Sweden. It is rare in children before the age of 10. During puberty the female to male ratio increases to be two to three times more common in females. The ratio remains constant until menopause and thereafter declines. LÄS MER

  3. 2. Radiobiological effects of the thyroid gland - transcriptomic and proteomic responses to 131l and 211At exposure

    Författare :Nils Rudqvist; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; astatine-211; iodine-131; radionuclide therapy; nuclear medicine; environmental exposure; thyroid; radiation biology; transcriptomics; proteomics; ionizing radiation; toxicity; normal tissue damage; microarray; LC-MS; biomarker;

    Sammanfattning : Radionuclides are widely used in medicine. 131I is one of the most employed radionuclides and is administered to patients either bound to tumor targeting molecules or as halide to target the thyroid or thyroid cancer. LÄS MER

  4. 3. Selenium and Breast Cancer. Is It Protective? Epidemiologic Evidence Regarding Risk and Prognosis

    Författare :Malte Sandsveden; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast neoplasms; Selenium; Epidemiology; cancer biomarkers; Single nucleotide polymophisms; Thyroid hormone receptor alpha; Dietary selenium intake; Serum selenium; Genetic Risk;

    Sammanfattning : .... LÄS MER

  5. 4. Genetic Characterization and Identification of Novel Treatment Targets in Anaplastic Thyroid Carcinoma

    Författare :Naveen Ravi; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaplastic thyroid cancer; copy number alterations; somatic mutations; mutational signatures; DNA methylation analysis; Gene expression analysis;

    Sammanfattning : Anaplastic thyroid cancer (ATC) is a rare and highly aggressive thyroid malignancy, usually resistant to conventional therapeutic strategies. The prognosis of ATC is extremely poor with a median survival rate of 6 months. Current treatment therapy includes surgical resection in combination with external radiotherapy and chemotherapy. LÄS MER

  7. 5. Tumour stromal and demographical factors affecting the metastatic aggressiveness of small differentiated papillary thyroid cancers in Sweden

    Författare :Haytham Bayadsi; Joakim Hennings; Malin Sund; Robert Bränström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Papillary thyroid cancer; Tumour stroma; Geographic information system; Register; Surgery; kirurgi;

    Sammanfattning : Background: The incidence of papillary thyroid cancer (PTC) has been increasing over the recent decades, especially that of small papillary thyroid cancers (sPTCs) (≤ 20mm in size). sPTCs are generally classified as low risk cancers with a very favourable diagnosis, yet some of these cancers still cause locoregional and distant metastasis, recurrence and even death. LÄS MER