Sökning: "Thuy Tran"

Hittade 3 avhandlingar innehållade orden Thuy Tran.

  1. 1. Thermostable Phytase from a Bacillus sp.: Heterologous Production, Mutation, Characterization and Assay Development

    Författare :Tran Thi Thuy; Bioteknik; []
    Nyckelord :ß-propeller phytase; recombinant protein; site-directed mutagenesis; phytate;

    Sammanfattning : Phytase is an important enzyme in the food/feed industry. It catalyzes the hydrolysis of phytate, an anti-nutrient compound present in cereals and grains, to release orthophosphate and myo-inositol-6-phosphate with lower degrees of phosphorylation. LÄS MER

  3. 2. Molecular Imaging of HER2 Expression using Synthetic Affibody Molecules : Design, Synthesis and Biological Evaluation

    Författare :Thuy Tran; Vladimir Tolmachev; Uwe Haberkorn; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN; Biomedical Radiation Science; biomedicinsk strålningsvetenskap;

    Sammanfattning : Molecular imaging is an emerging multidisciplinary field that addresses the visualisation of diseases at the cellular and molecular levels. This thesis focuses on the development of a synthetic Affibody molecule-based imaging tracer for the detection of HER2 expression in malignant tumours. LÄS MER

  4. 3. Compact-disc microfluidic methods for characterization of therapeutic antibodies : Analysis of post-translational modifications

    Författare :Thi Thuy Tran; Gunnar Thorsén; McLean John; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microfluidic CD; therapeutic antibodies; post-translational modifications; glycosylation profiling; multivariate statistical analysis; MALDI-MS; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Characterization of post-translational modifications (PTMs) of therapeutic proteins is very important during the bioprocess development to maintain desired product quality and during the submission process to regulatory authorities for product approval. Monitoring glycosylation in pharmacokinetic studies can be useful to evaluate the dependence of clearance rates on different glycoforms. LÄS MER