Avancerad sökning

Hittade 5 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Thromboinflammation : in a Model of Hepatocyte Transplantation

    Författare :Elisabet Gustafson; Bo Nilsson; Staffan Meurling; Ewa Ellis; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Hepatocyte transplantation is an attractive method for the treatment of metabolic liver disease and acute liver failure. The clinical application of this method has been hampered by a large initial loss of transplanted cells. LÄS MER

  3. 2. The role of the thromboinflammatory response under hemolytic conditions : pathophysiological mechanisms and therapeutic inhibition

    Författare :Alexandra Gerogianni; Per H. Nilsson; Camilla Mohlin; Tom Eirik Mollnes; Kristina Nilsson Ekdahl; Mihály Józsi; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hemolysis; heme; thromboinflammation; biomaterials; complement inhibition; LVAD; IONPs; Biomedical Sciences; Biomedicinsk vetenskap; Immunologi; Immunology;

    Sammanfattning : In blood circulation, the complement and the coagulation cascades, together with platelets and endothelial cells form a complex network of crosstalk. When dysregulated, these interactions can lead to inflammation in combination with thrombosis (thromboinflammation) and the manifestation of pathophysiological complications. LÄS MER

  4. 3. Vascular Interactions in Innate Immunity and Immunothrombosis: : Models of Endothelial Protection

    Författare :Sofia Nordling; Peetra Magnusson; Paul Kubes; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endothelial cells; Thrombosis; Innate immunity; Immunothrombosis; Thromboinflammation; Immunologi; Immunology;

    Sammanfattning : The phenomenon known as immunothrombosis has garnered increased attention over the last few years. Much work has been done to characterize the cross talk between hemostasis and the innate immune system. LÄS MER

  5. 4. Regulation of thromboinflammation in therapeutic medicine : Special focus on surface coating strategies

    Författare :Sana Asif; Bo Nilsson; Christine Skerka; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Biomaterials are an integral part of modern health care and offer potential treatment modalities to diseases and conditions otherwise intractable. However, the critical issue herein is incompatibility reactions. LÄS MER

  7. 5. SURFACE PROPERTIES OF IMPLANTS MANUFACTURED USING ELECTRON BEAM MELTING

    Författare :Rebecca Klingvall Ek; Lars-Erik Rännar; Mikael Bäckström; Jaan Hong; Felicia Suska; Mittuniversitetet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; electron beam melting; blood coagulation; bone ingrowth; surface roughness; process parameters;

    Sammanfattning : This thesis summarizes the results concerning the manufacture of medical implants for bone replacement using electron beam melting (EBM) which is an additive manufacturing (AM) technology, and aims to satisfy the engineering needs for the medical functionality of manufacturing technology. This thesis has focused on some microscopic properties for surfaces and bone integration. LÄS MER