Sökning: "Thomas von Zglinicki"

Hittade 1 avhandling innehållade orden Thomas von Zglinicki.

1. 1. Mechanisms of lipofuscin/ceroid accumulation and its impact on the function of the lysosomal system

   Författare :Alexei Terman; Thomas von Zglinicki; Linköpings universitet; []
   Nyckelord :Aging; Autophagocytosis; Centrophenoxine; Ceroid; Lipofuscin; Lysosomes; Oxidative stress; MEDICINE; MEDICIN;

   Sammanfattning : The accumulation of lipofuscin - an electron-dense, autofluorescent, polymeric, intralysosomal substance - is a recognized hallmark of aging postmitotic cells. Ceroid- a substance very close, or perhaps even identical, to lipofuscin - is a characteristic of various pathological processes, such as lysosomal storage diseases, malnutrition, atherosclerosis, oxidative stress, ionizing radiation, etc. LÄS MER