Avancerad sökning

Hittade 4 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Thermodynamics of protein-DNA interactions

    Författare :Thomas Lundbäck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DNA-protein interactions; molecular recognition; thermodynamics; specificity.dehydration; salt dependence.;

    Sammanfattning : This thesis treats the molecular recognition between DNA-binding proteins and DNA and the way these interactions are affected by the surrounding water solution and dissolved solutes. The work involves studies on the thermodynamics of sequence specific DNA-binding of the human glucocorticoid receptor DNA-binding domain and the nonsequence specific DNA- binding of Sso7d from the archaeon Sulfolobus solfataricus. LÄS MER

  3. 2. Longterm performance of polyolefins in different environments including chlorinated water: antioxidant consumption and migration and polymer degradation

    Författare :Marie Lundbäck; Ulf Gedde; Thomas Hjertberg; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chemical engineering; polyethylene; polybutylene; HDPE; LLDPE; phenolic antioxidants; oxidation induction time OIT ; migration; chlorinated water; pressure testing; lifetime; chemical consumption.; Kemiteknik; Chemical engineering; Kemiteknik;

    Sammanfattning : The long-term performance of stabilized polyolefins in different environments was studied with focus on antioxidant consumption and migration. Plaques of linear polyethylene (LPE) and branched polyethylene (BPE) were stabilized with Santonox® R (4,4'-Thiobis(6-tert-butyl-3-methylphenol)), Irganox® 1081 (2,2’-Thiobis(4-methyl-6-tertbutylphenol)), or Lowinox® 22M46 (2,2’-Methylenebis(6-tert-butyl-4-methylphenol)). LÄS MER

  4. 3. Epidemiology of asthma in primary school children

    Författare :Anders Bjerg Bäcklund; Eva Rönmark; Bo Lundbäck; Thomas Sandström; Giovanni Viegi; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; wheeze; child; allergic sensitisation; prevalence; remission; risk factor; trend; Lung diseases; Lungsjukdomar;

    Sammanfattning : Background: Childhood asthma has increased worldwide, although recent studies report a prevalence plateau in some western countries.Aims: To investigate the prevalence of asthma and the associated risk factor patterns from ages 7-8 to 11-12 with special emphasis on the hereditary component, and further to study prevalence trends at age 7-8 from 1996 to 2006 and the possible determinants of these trends. LÄS MER

  5. 4. Characterizing phenotypes of Mycobacterium tuberculosis and exploring anti-mycobacterial compounds through high content screening

    Författare :Sadaf Kalsum; Maria Lerm; Thomas Lundbäck; Annika Jenmalm; Lena Serrander; Priscille Bordin; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Tuberculosis (TB), an airborne disease and one of the top 10 causes of death globally, is caused by Mycobacterium tuberculosis (Mtb). Current standard therapy for TB treatment includes multiple drugs for a period of at least 6 months. LÄS MER