Sökning: "Thomas H. Tötterman"
Hittade 3 avhandlingar innehållade orden Thomas H. Tötterman.
1. TARP Promoter-Based Prostate Cancer Gene Therapy : From Development to Application
Sammanfattning : Prostate cancer is one leading cause of cancer-related death among men in Western countries. The standard therapies for localized prostate cancer include radical prostatectomy and radiation therapy. Such measures are relatively effective in the short term, but many patients ultimately relapse. LÄS MER
2. Adenovirus-mediated Gene Therapy of Prostate Cancer
Sammanfattning : Adenovirus-mediated gene therapy is a potential complement to standard cancer treatments. Advantages are that vectors can be used to target tumors and that replicating viruses lead to increased therapeutic dosage. LÄS MER
3. Adenovirus-mediated CD40 Ligand Immunotherapy of Prostate and Bladder Cancer
Sammanfattning : Cancer immunotherapy aims at reversing the immunosuppressive tumor environment and enhancing anti-tumor immunity. This thesis comprises studies on murine models for prostate (TRAMP-C2) and bladder (MB49) cancer with the aim to explore if the introduction of an adenoviral vector expressing CD40 ligand (AdCD40L) can induce anti-tumor immune responses. LÄS MER