Sökning: "Thioredoxin Trx"

Visar resultat 1 - 5 av 34 avhandlingar innehållade orden Thioredoxin Trx.

  1. 1. Regulation of growth, differentiation and survival of B-chronic lymphocytic leukemia cells

    Författare :Ola Söderberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; B-CLL; B cells; IL-2; IL-4; IL-10; IL-15; CD40-stimulation; SAC; Thioredoxin; proliferation; differentiation; survival; in vitro; EBV; Patologi; Pathology; Patologi; Pathology; patologi;

    Sammanfattning : Chronic lymphocytic leukemia of B cell type (B-CLL) is the most commonform of leukemia in the Western countries. The signals regulating theexpansion of the B-CLL clone in vivo is yet far from being fully understood. LÄS MER

  3. 2. Studies on Redox-proteins and Cytokines in inflammation and Cancer

    Författare :Akter Hossain; Anders Rosén; Christer Lindqvist; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thioredoxin Trx ; Selenium; Tumor necrosis factor TNF ; Cancer; nflammation; oxidative stress; Protein-disulfide isomerase PDI ; Tumor necrosis factor receptor TNFR ; Medical cell biology; Medicinsk cellbiologi;

    Sammanfattning : The redox state in the cell plays a major role in determining vital functions and its major imbalance can lead to severe cell injury or death. Redox active proteins and cytokines involved in this process includes thioredoxin (Trx), protein disulfide isomerase (PDI), and tumor necrosis factor (TNF) superfamilies. LÄS MER

  4. 3. Thioredoxins and gene regulation in the Drosophila germline

    Författare :Malin J. Svensson; Jan Larsson; David Roberts; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; thioredoxin; sex-specific; Pof; chromosome 4; gene regulation; kromosom 4; genreglering; Drosophila; thioredoxin; könsspecifik; Pof; Molecular biology; Molekylärbiologi;

    Sammanfattning : Spermatogenesen är i många organismer en av de mest dramatiska förvandlingar som en cell kan genomgå – en vanlig, rund, diploid cell omvandlas till en nålformad, haploid cell med ett tätt packat cellmaskineri. I bananfluga, Drosophila melanogaster, innebär denna process flera karaktäristiska stadier. LÄS MER

  5. 4. Functional characterization of cytosolic and mitochondrial thioredoxin reductases

    Författare :Ivan Nalvarte; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Thioredoxin; thioredoxin reductase; reactive oxygen species; mitochondria; differentiation; redox signaling; ubiquinone; cytochrome c; selenium; selenoprotein.;

    Sammanfattning : Mammalian thioredoxin reductases (TrxRs) are homodimeric selenoproteins belonging to the nucleotide oxidoreductase family. They contain a C-terminal penultimate selenocysteine residue, which is kept reduced by the N-terminal redox active site, CVNVGC, of the adjacent subunit. LÄS MER

  7. 5. Immunological Studies in Malignant Melanoma : Importance of TNF and the Thioredoxin System

    Författare :Anna-Maria Barral; Anders Rosén; R. Kiessling; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Malignant melanoma is a tumor whose incidence is dramatically increasing in persons with light-coloured skin in all parts of the world. Due to its resistance against traditional chemo- and radiotherapy, melanoma has been a favourite target of alternative therapies, in particular those involving immunological mechanisms. LÄS MER