Sökning: "Thiol-disulfide oxidoreductase"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Thiol-disulfide oxidoreductase.

  1. 1. Studies on Thiol-Disulfide Oxidoreductases in Bacillus subtilis

    Författare :Mirja Carlsson Möller; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; Microbiology; bacteriology; bacterial sporulation; endospore; thioredoxin; Thiol-disulfide oxidoreductase;

    Sammanfattning : Bacillus subtilis is a model organism for endospore-forming gram-positive bacteria. Endospores are formed in response to nutrient starvation. They can resist harsh environments and last for long periods of time. Once nutrients again become available, the endospore can germinate and the vegetative life cycle be resumed. LÄS MER

  3. 2. Purification and characterization of thioltransferase (thiol: disulfide oxidoreductase) from rat liver cytosol : studies on its substrate specificity and possible biological role

    Författare :Kent Axelsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This investigation describes an enzyme» from rat liver cytosol» catalyzing thiol-disulfide exchange reactions. The purification of the enzyme as well as many of its molecular characteristics are presented. LÄS MER

  4. 3. Structure-function studies of glutaredoxins and related oxidoreductases

    Författare :Tobias Elgán; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Thiol-disulfide oxidoreductase; thioredoxin; Trx; glutaredoxin; Grx; protein disulfide oxidoreductase; PDO; -C-X-X-C-; specificity; conformational stability; ligandinduced stability; CD spectroscopy; redox potential;

    Sammanfattning : The members of the ubiquitous group of thiol-disulfide oxidoreductases are characterized by a conserved tertiary structure, the thioredoxin (Trx) fold, and by having a consensus -C-X-X-C- active site sequence motif. By utilizing the active site cysteines, these proteins participate in redox reactions by catalyzing reversible disulfide oxidation and reduction. LÄS MER

  5. 4. On the role of penicillin-binding protein SpoVD in endospore cortex assembly

    Författare :Ewa Bukowska-Faniband; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sporulation; cortex; Bacillus subtilis; penicillin-binding proteins; SpoVD; peptidoglycan;

    Sammanfattning : Bacteria of the genera Bacillus and Clostridium can form endospores as a strategy to survive unfavourable environmental conditions. Endospore formation involves synthesis of cortex, a thick layer of modified peptidoglycan that surrounds the spore. LÄS MER

  7. 5. In vivo functions of mammalian glutaredoxin 2

    Författare :Maria Lönn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Oxygen is essential for all respirating life forms. However, the use of molecular oxygen as terminal electron acceptor of the respiratory electron chain leads to the generation of reactive oxygen species (ROS) as product of incomplete oxygen reduction. To different extends, ROS can react with and damage DNA, lipids and proteins. LÄS MER