Sökning: "Therapy resistance"

Visar resultat 6 - 10 av 436 avhandlingar innehållade orden Therapy resistance.

  1. 6. Clostridium difficile : epidemiology and antibiotic resistance

    Författare :Torbjörn Norén; Erik Bäck; Lars G. Burman; Roland Möllby; Örebro universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Clostridium difficile; antibiotic resistance; epidemiology; Medicine; Medicin; Medicin; Medicine;

    Sammanfattning : Clostridium difficile is a spore-forming toxin-producing intestinal bacterium abundant in soils and waters. This pathogen relies on increased growth by a disturbed intestinal microflora and the production of two cytotoxins, toxin A and toxin B, which may cause anything from mild self-limiting C. LÄS MER

  3. 7. β-lactam combinations against multidrug-resistant Enterobacterales : Exploring combination effects and resistance development

    Författare :Lisa Allander; Thomas Tängdén; Linus Sandegren; Pernilla Lagerbäck; Arnfinn Sundsfjord; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gram-negative bacteria; antibiotic combination therapy; antibiotic resistance; beta-lactams; beta-lactamase inhibitors; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : The β-lactam antibiotics are a cornerstone in treating bacterial infections, but the increasing prevalence of antibiotic resistance worldwide threatens their effectiveness. The main driver of β-lactam resistance is the production of β-lactamases, which are bacterial enzymes that inactivate the antibiotic. LÄS MER

  4. 8. Pharmacokinetic and Pharmacodynamic Modeling of Antibiotics and Bacterial Drug Resistance

    Författare :Ami Fazlin Syed Mohamed; Lena Friberg; Teresa Dalla Costa; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; pharmacokinetics; pharmacodynamics; modeling; antibiotics; resistance; combination; Gram-negative bacteria; gentamicin; colistin; meropenem; newborn infants; critically ill patients; Infectious Diseases; Infektionssjukdomar; Pharmaceutical Science; Farmaceutisk vetenskap;

    Sammanfattning : Exposure to antibiotics is an important factor influencing the development of bacterial resistance.  In an era where very few new antibiotics are being developed, a strategy for the development of optimal dosing regimen and combination treatment that reduces the rate of resistance development and overcome existing resistance is of utmost importance. LÄS MER

  5. 9. Urinary tract infections in primary health care in northern Sweden : epidemiological, bacteriological and clinical aspects

    Författare :Sven Ferry; Bengt Mattsson; Lars Burman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urinary tract infection UTI ; primary health care PHC ; epidemiology; clinical presentation; bacteriuria diagnosis; bacteriology; drug resistance; therapy;

    Sammanfattning : The epidemiology of urinary tract infection (UTI) in the population of Vännäs (8 000 inhabitants) was studied during one year. The annual incidence increased from 0.5% in the first decade of life to more than 10% in the age group 90-100 years. LÄS MER

  7. 10. Muscle strength and resistance exercise in women with fibromyalgia-a person-centred approach

    Författare :Anette Larsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physical Therapy; Fibromyalgia; Muscle Strength; Resistance Exercise; Person-centred care; ;

    Sammanfattning : Fibromyalgia (FM) is characterized by generalized pain and associated with impaired physical capacity and activity limitations. Low-intensity exercise has been shown to be a safe way to exercise without risking an increase in diseasespecific symptoms. LÄS MER