Sökning: "Th1"
Visar resultat 6 - 10 av 259 avhandlingar innehållade ordet Th1.
6. Th1, Th2 and Treg associated factors in relation to allergy
Sammanfattning : Background: Immune responses are often divided into T helper 1 (Th1), Th2 and Treg like immunity. Allergy is associated with Th2 like responses to allergens and possibly to reduced regulatory functions. LÄS MER
7. Feeding Lactobacillus paracasei ssp. paracasei strain F19 to infants during weaning : effects on adaptive immunity and gut microbial function
Sammanfattning : Introduction: Gut microbial composition has been associated with immune-mediated diseases. Breastfeeding yields a microbiota rich in bifidobacteria and promotes colonization by lactobacilli. Bifidobacteria and lactobacilli are considered health-promoting and are used as probiotics, i.e. LÄS MER
8. Mercury-induced autoimmunity : Genetics and immunoregulation
Sammanfattning : The existence of immune self-tolerance allows the immune system to mount responses against infectious agents, but not against self-molecular constitutes. Although self-tolerance is a robust phenomenon, in some individuals as well as in experimental models, the self-tolerance breaks down and as a result, a self-destructive autoimmune disease emerges. LÄS MER
9. Innate and acquired immunity to herpes simplex virus type 2 glycoprotein G in humans
Sammanfattning : Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the human genital tract mucosa and is the most common cause of genital ulcer disease in humans. The infection exhibits a broad clinical spectrum, ranging from severe recurrent episodes of genital herpes to being completely asymptomatic. LÄS MER
10. Systemic sclerosis : vascular, pulmonary and immunological aspects
Sammanfattning : In systemic sclerosis (SSc), interstitial lung disease (ILD) and engagement of the vascular system lead to increased morbidity and mortality. The aim of this thesis was to elucidate, in a consecutively included cohort of SSc (limited and diffuse) patients (n = 33), the T cell cytokine profile driving the disease in ILD and to explore the role of matrix metalloproteinase 9 (MMP-9) and its inhibitor: tissue inhibitor of metalloproteinase 1 (TIMP-1) in the extracellular matrix (ECM) degrading process leading to fibrous scarring and honey combing. LÄS MER