Sökning: "Tempol"

Hittade 5 avhandlingar innehållade ordet Tempol.

  1. 1. Modulation of neutrophil extracellular trap formation in health and disease

    Författare :Ava Hosseinzadeh; Constantin F. Urban; Carol Munro; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; Candida albicans; Adenosine; Tempol; Nicotine; molekylärbiologi; Molecular Biology;

    Sammanfattning : The critical prompt innate immune response is highly built upon the influx of neutrophils from the blood stream to the site of infection. In the battlefield, neutrophils sense pathogen-associated molecular patterns (PAMPs) through their pattern-recognition receptors (PRRs) to launch a number of responses with the goal to defeat the invading pathogen. LÄS MER

  3. 2. Candida albicans adaption to host microenvironments drives immune evasion

    Författare :José Pedro Lopes; Constantin F. Urban; Alistair Brown; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fungi; candida albicans; neutrophils; mast cells; immune evasion; mycoses; infectious diseases; immunologi; Immunology; Infectious Diseases; infektionssjukdomar; Molecular Immunology; molekylär immunologi;

    Sammanfattning : Immunosuppressed patients are frequently afflicted with severe mycoses caused by opportunistic fungal pathogens. Besides being a commensal colonizing predominantly skin and mucosal surfaces, Candida albicans is the most common human fungal pathogen. LÄS MER

  4. 3. Physiological aspects of the glomerular filtration barrier

    Författare :Kristinn Sverrisson; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Proteinuria is associated with progression of kidney disease and is an independent risk factor for cardiovascular morbidity and mortality. The pathophysiological alterations resulting in proteinuria are obscure, although proteinuria is often associated with pathological changes in the glomerular filtration barrier (GFB). LÄS MER

  5. 4. Renal hemodynamics in renal artery stenosis and angiotensin II-dependent hypertension. Pathophysiological and diagnostic aspects

    Författare :Aso Saeed; Göteborgs universitet; []
    Nyckelord :angiotensin II; autoregulation of renal blood flow; color duplex sonography; endothelin-1; oxidative stress; renal artery stenosis; renal hemodynamics; renovascular hypertension;

    Sammanfattning : Patients with renovascular hypertension have a poor renal and cardiovascular prognosis. To improve the care of these patients, we need to increase knowledge about the pathophysiological mechanisms involved. LÄS MER

  7. 5. Astrocytic communication and cell death during metabolic depression and oxidative stress

    Författare :Christina Nodin; Göteborgs universitet; []
    Nyckelord :astrocyte; gap junction; ATP; ROS; oxidative stress; Annexin V; AIF; programmed cell death; Nrf2; scavenger; iodoacetate; SIN-1;

    Sammanfattning : Stroke is a major cause of death and adult disability in the western world. Most often, stroke is caused by the occlusion of a brain artery. Within the perfusion territory of the occluded vessel, various degrees of necrotic and delayed programmed cell death will occur if the occlusion persists, leading to expanding tissue damage. LÄS MER