Sökning: "Tatiana L. Steiler"

Hittade 1 avhandling innehållade orden Tatiana L. Steiler.

1. 1. Kinase cascades in the regulation of glucose homeostasis

   Författare :Tatiana L Steiler; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Skeletal muscle; insulin resistance; T2DM; hyperglycemia; high fat diet; glucose transport; PI3K-; MAPK- and AMPK-signaling pathways; AMPKgamma3;

   Sammanfattning : Therapeutic strategies to treat Type 2 Diabetes Mellitus (T2DM) aim at improving muscle insulin sensitivity by either directly modulating, or bypassing defective insulin signaling. Insulin induces metabolic and gene regulatory responses via PI 3-Kinase (PI3K) and Mitogen-Activated Protein Kinase (MAPK) signaling pathways, respectively. LÄS MER