Sökning: "Tat"

Visar resultat 6 - 10 av 45 avhandlingar innehållade ordet Tat.

  1. 6. REGULATED UPTAKE OF BIOPOLYMERS Role of cell surface proteoglycans Implications for drug and gene delivery

    Författare :Staffan Sandgren; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Cytology; oncology; proliferation; differentiation; Medicine human and vertebrates ; growth factor; cancer; drug delivery; gene therapy; LL-37; HIV-Tat; cell penetrating peptides; polyamines; heparan sulfate; onkologi; Cytologi; cancerology; internalization; proteoglycans;

    Sammanfattning : Cells continuously export, import, and recycle molecules over the plasma membrane. Internalization, i.e. cellular import of extracellular material, is a fundamental process, which provides cells with nutrients and enables the immune cells of higher organisms to remove debris, sample their surroundings for antigens and to fight microbes. LÄS MER

  3. 7. Studies in DNA immunization

    Författare :Cecilia Svanholm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Chlamydia pneumoniae; DNA vaccine; GM-CSF; HIV-1; hsp60; Nef; Rev; Tat; signal sequence;

    Sammanfattning : This thesis describes investigations and developments of DNA immunization techniques, which were applied in the study of two different pathogens; HIV-1 and Chlamydia pneumoniae. DNA vaccines, i.e. naked plasmid DNA encoding an antigen, represent a novel strategy for generating protective immunity against several infectious diseases. LÄS MER

  4. 8. Regulation of gene and protein expression : two model systems

    Författare :Lars H Lund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; EIAV; Tat; TAR; Cyclin T1; CDK9; P-TEFb; RNA polymerase II; gene regulation; transcriptional elongation; CEA; signal sequence.;

    Sammanfattning : Genetic information is expressed by DNA transcription and mRNA translation. With few exceptions, every cell of an organism, or the human body, contains the same genetic information. Yet the structure and function of different tissues are highly variable. LÄS MER

  5. 9. Test Cost Reduction of 3D Stacked ICs : Test Planning and Test Flow Selection

    Författare :Breeta Sengupta; Integrerade elektroniksystem; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; 3D Stacked Integrated Circuits 3D SIC ; Test Cost; Optimization; Test Flow; Design for Test DfT ; Test Application Time TAT ;

    Sammanfattning : Ever higher levels of integration within the Integrated Circuit (IC) tomeet progressively widening scope of its application in respect of functionality,size, performance and manufacturing issues inspired developmentof the three-dimensional (3D) Stacked IC as a device havingviable architecture. However, with increased complexity, manufacturingcost increased. LÄS MER

  7. 10. Essays in empirical corporate finance

    Författare :Joakim Bång; Handelshögskolan i Stockholm; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Sammanfattning : In the first of the three chapters in this thesis, the effects of overlapping board directorships on executive compensation are analyzed. In particular the possibility of more or less explicit agreements to reciprocally increase compensation levels, or the possibility that the personal relationships of board members and CEOs determine compensation levels are examined, with suggestive results. LÄS MER