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Visar resultat 11 - 15 av 45 avhandlingar innehållade ordet Tat.
11. Ligand-induced structural changes in HIV-1 envelope glycoprotein
Sammanfattning : The first step in HIV-1 entry is the interaction between viral envelope glycoprotein gp120 and CD4 receptor on permissive host cells. The interaction initiates a series of sequential conformational rearrangements that exposes epitopes involved in interaction with co-receptors. LÄS MER
12. Inflammation and Coagulation Activity in Unstable Coronary Artery Disease and the Influences of Thrombin Inhibition
Sammanfattning : In patients with unstable coronary artery disease, this study evaluated the degree of inflammation and coagulation activity, relations to myocardial cell damage, prognosis, and influences of randomisation to 72 h infusion with three different doses of inogatran, a direct thrombin inhibitor (n=904), or unfractionated heparin (n=305). Anticoagulant treatment effects were evaluated with aPT time. LÄS MER
13. Virulence mechanisms of pathogenic Yersinia : aspects of type III secretion and twin arginine translocation
Sammanfattning : The pathogenic bacteria Yersinia pestis and Y. pseudotuberculosis are related to the degree where the former is considered a subspecies of the latter, and still they cause disease of little resemblance in humans. Y. pestis is the causative agent of lethal bubonic and pneumonic plague, while Y. LÄS MER
14. Platelet Activation and Inhibition in Connection with Vascular Stents
Sammanfattning : This thesis describes the Chandler loop, which makes it possible to conduct studies in vitro of molecular and cellular interactions between whole blood and stents. It was possible to monitor activation and inhibition of the cascades systems, leukocytes and platelets by combining different platelet inhibitors and heparin coating of stents. LÄS MER
15. Coagulation, fibrinolysis and inflammation in open surgery for infrarenal abdominal aortic aneurysm
Sammanfattning : Elective repair of infrarenal abdominal aortic aneurysm (AAA) carries a mortality of 4-8% and there is a substantial incidence of serious non-lethal complications. During surgery there is a situation of relative ischaemia and subsequent reperfusion of the lower part of the body. LÄS MER